REACTIONSOF THEOPHYLLINES. CHEMICAL CONVERSIONS OF 8-AMINOTHEOPHYLLINATES !. !. Kuz'menko and T. V. Zvolinskaya Thelvnallv stable, colored 8-aminotheophyllinates (hetaine derivatives o[ theophylline).[hlwl unstable, colorless salts with strong mineral acids and tmdergo partial decomposition to a uric acid upon plvlonged rcffhtxing with concentrated base solution. Substituted 8-pyridinium theophyllinates readily take part in tvpic'al reactions ~?/' the./imctional grotq~ in the substituted pyridine ring with retention r?/" the hetaine .~'truc'ture. The /ormation o/'the ,~Tnthesized compounds was coq/ilwwd by IR and NMR .wectroscot~y.
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ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract Heating of 8-bromotheophylline (I) with 2-isocyanato-1,3,2-benzodioxaphosphole 2-oxide in pyridine (II) gives the betaine (III) instead of the expected carbamoyl derivative.
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