Reactions of theophyllines. Chemical conversions of 8-aminotheophyllinates

Abstract

REACTIONSOF THEOPHYLLINES. CHEMICAL CONVERSIONS OF 8-AMINOTHEOPHYLLINATES !. !. Kuz'menko and T. V. Zvolinskaya Thelvnallv stable, colored 8-aminotheophyllinates (hetaine derivatives o[ theophylline).[hlwl unstable, colorless salts with strong mineral acids and tmdergo partial decomposition to a uric acid upon plvlonged rcffhtxing with concentrated base solution. Substituted 8-pyridinium theophyllinates readily take part in tvpic'al reactions ~?/' the./imctional grotq~ in the substituted pyridine ring with retention r?/" the hetaine .~'truc'ture. The /ormation o/'the ,~Tnthesized compounds was coq/ilwwd by IR and NMR .wectroscot~y.

BF3@K10: An Efficient Heterogeneous Montmorillonite Catalyst for the Halogenation of N-Heterocycles

“…In 2014, Bamoniri and coworkers developed a green heterogeneous solid acid based on BF3 embedded in silica nanoparticles for preparing formazan dyes under solvent-free conditions 7 . Similarly, silica-supported boron trifluoride (SiO2.BF3) was used as a catalyst for the synthesis of 14-aryl or alkyl-14H-dibenzo[a,j]xanthene derivatives by condensation of 2-naphthol and aldehydes 8 . The same heterogeneous catalyst was used to prepare 1,2,4,5tetrasubstituted imidazoles 9 .…”