We studied the effects of pharmacological blockade (by injections of naloxone) of the system of opioid peptides on changes in emotional/behavioral reactions of rats in the open-field test. These changes were caused by the isolated action of low-intensity electromagnetic radiation (EMR) of extrahigh frequency (EHF) and its combination with experimentally induced hypokinetic stress. We conclude that one of the mechanisms of physiological effects of low-intensity EHF EMR is an increase in the functional activity of the system of regulatory opioid peptides; this results in adaptive modifications of the emotional/behavioral reactions under new conditions of the open-field test and provide an anti-stress effect under conditions of hypokinetic stress.
We examined the modifying effect of hypokinetic stress on the duration of behavioral phenomena in rats under conditions of experimentally induced tonic somatic, visceral, acute thermal, and electrostimulationevoked pain. Stress of the above type (hypokinetic) was found to modify the pain sensitivity in rats related to all tested types of pain stresses of different etiology. Changes in the pain sensitivity of the animals under conditions of experimental pain tests depended on the duration of mobility restriction and could demonstrate opposite directions.
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