Technique for endoscopic examination of the extent of gastritis in upper portion of the stomach was established with congo red solution. Gastritis in upper portion of the stomach was then examined by this technique and in resected stomachs. The results was as follows: 1. By means of congo red test, it is possible to demonstrate the extent of gastritis in the upper stomach as "non-discolored area" characterized by absence of acid secretion.2. Histological characteristics of gastritis in the upper stomach consisted mainly of atrophy of fundic glands and intestinal metaplasia, while epithelial defect, edema, inflanimatory cell infiltration and hyperemia were also detected. 3. Two different modes of gastritic extension were recognized: one in which gastritis spreads from the lower corpus to cardiac side, and the other in which it begins on the cardiac side and spreads to the lower. 4. Gastritis starting on the cardiac side, grows with aging, and the histological changes were advance of fundic gland's atrophy and intestinal metaplasia.

The extension and histological changes of fundal gastritis were investigated by endoscopic congo red test, combined with gastric biopsy under direct vision, and obtained the following results.

No abstract

No abstract

No abstract