Role of limbic system, first of all, hippocampal formation, is carefully analyzed in literature because of its involvement in different psychiatric diseases. Results are contradictory, may be because of insufficient data of normal volumes of structures involving in cognitive and affective functioning of the brain. Hippocampus is very complex organized structure consisting of different subfields and subregions which probably differently changes in different psychiatric diseases. Aim of our study was to analyzed changes in volumes of the whole hippocampus, its subregions and subfields in different psychiatric diseases. In our study we have analyzed MRI morphometry of hippocampal formation in healthy volunteers, patients with Alzheimerdisease (AD) in early stage, vascular dementia (VD), depression based on medical literatureandourexperience. Patients were divided on 4 groups: 10 patients with early Alzheimer disease, 10 normal volunteers, 10 patients with vascular dementia and 10 patients with depression. We have determined method of definition and volume evaluation of different hippocampal subfields. We find difference in the volumes of CA3, molecular stratum and fascia dentatain early stage of AD; in the volume of hippocampal tail, molecular stratum of fascia dentataand CA3 in patients with VD; in molecular stratum of fasciadentata, fimbria and CA3 in patients with depression because of role of these fields in coordination of hippocampal activity.
In our study we have analyzed MRI of mediobasal parts of temporal lobes in healthy volunteers and patients with Alzheimer disease in early stage based on medical literature and our experience. We have determined method of defnition and volume evaluation of different hippocampal subfelds.
The pandemic of the new coronavirus infection (COVID-19) has contributed to an increase in problems related to eating behavior and body image in the population. Various risk factors that have become relevant due to changes in the usual lifestyle have significantly affected the frequency of eating disorders in the adolescent population. This necessitated the adapting of new strategies for providing medical care in conditions of limited personal contact.The aim of the work is the methodological substantiation and systematization of modern approaches to the prevention and treatment of eating disorders, body image disorders and risk factors associated with them in adolescents in the conditions of the COVID-19 pandemic.Materials and methods. The methodological basis of the work is a comprehensive analysis of modern medical and social approaches and recommendations on the organization of assistance to adolescents with eating disorders and body image disorders, with a description of personal experience of using various interventions on an outpatient basis during the pandemic.Results: Prevention and treatment of eating disorders and body image disorders in adolescents during the pandemic should be aimed at specific risk factors those have proved to be the most relevant in connection with restrictive measures: involvement in body image-related social media content and active use of the media; reduction of physical activity with simultaneous increase in access to food; social isolation and reduction of social support; restriction of access to qualified care. The most reasonable approaches during the pandemic are the approaches focused on the family of a teenager using, if possible, remote forms of assistance.Conclusions: Currently, there are no norms and standards in the organization of assistance to adolescents with eating disorders and body image disorders in the pandemic context. However, the analysis of the implemented approaches aimed at various risk factors of these disorders will allow the use of the most effective preventive and therapeutic practices in the future.
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