Background: Live related kidney transplantation is the most preferred form of renal replacement therapy worldwide including Bangladesh. However, it is challenging and also rewarding both for patients and treating physicians. BSMMU hospital has given maximum effort for its greater success. The aim of this study was to share our ten years’ experience regarding some aspects of live related renal transplantation. Methods: This retrospective study was conducted in nephrology department of BSMMU hospital from January 2002 to December 2015. Data were collected from hospital records and some previously conducted study on these transplant recipients. Results: A total of 360 live related kidney transplant recipients were evaluated during this period. Recipients Male: Female ratio was 1.57:1. Mean age of recipients were 39.58 ± 10.46 years. The causes of ESRD were chronic glomerulonephritis 220(61.60 %), diabetic nephropathy 58(16.24%), hypertensive nephrosclerosis 22 (6.16 %), chronic interstitial nephritis 11 (3.08 %), SLE 10(2.8%), ADPKD 6(1.68 %), unknown 19(5.32 %). Most of the donors were mother (21.84% %) followed by spouse mostly wife (20.44%) and sister (18.76 %). Almost all recipients were on MHD 352(97.78%), 2 were on CAPD and 06 were pre-emptive transplantation. Triple immunosuppressive protocol Cyclosporine or Tacrolimus, MPA or Azathioprine and Prednisolone were used in each patient. Recipients with poor HLA matching received Baciliximab in standard dose. CMV prophylaxis was given in selected patients and each patient received pneumocystis jirovecii prophylaxis. Common complications during post-operative period were ATN 41(11.48%), DGF 23(6.44%), Acute rejection 50(14%) and infection mainly urinary tract infection 46(12.88%) and RTI 14(3.92) followed by wound infection and other surgical complication. Presence of BK virus infection was studied in 29 transplant recipient and it was found to be positive in 6(20.7%) cases. Protocol biopsy was done in 37 transplant recipient in the 2008-2009 on day 14, and day 90 to see subclinical rejection and early graft dysfunction. On day 14th biopsy report showed 21(56.7%) normal histology, 5(13.5%) had subclinical rejection, 5(13.5%) had clinical rejection, 4(10.8 %) developed ATN, 2(5.2 % ) cyclosporine toxicity, and report at 3 month showed normal histology 18(48.60%), subclinical rejection 7(18.90%), clinical rejection 5(10.80%). Leading cause of chronic allograft dysfunction was chronic allograft nephropathy (CAN) 60(19.80%) followed by chronic cyclosporine toxicity 37(12.21%) and de-novo or recurrent glomerulonephritis. Mean post-transplant hospital stay was 18.46 ± 5.56 days. Mean duration of normalization of serum creatinine after surgery was 7.38 ± 3.88 days. At discharge 74.40% patients had normal renal function with mean serum creatinine 1.10 ± 0.26 mg/dl and 21.34% patients showed gradual improvement of renal function with mean serum creatinine 2.12 ± 0.97 mg/dl. In our study 1 year and 5 years’ graft survival was 93.88% and 75.16% respectively and 1 year and 5 years’ patient’s survival was 346(96.08%) and 290(81.2%). Conclusion: Our report shows that short and long term graft and patient survival is encouraging and comparable to other centers of both developing and some developed countries with limited resources and facilities.

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Background: Impaired fasting glucose (IFG) is a prediabetic condition and is a high-risk state for developing diabetes and associated complications. The aim of this study was to explore the association of vitamin D with insulin secretory function among the IFG subjects. Materials and Methods: This was a prospective cross-sectional study conducted in the

Background: Covid-19 imposes a serious public health pandemic affecting the whole world, as it is spreading exponentially. Besides its high infectivity, SARS-CoV-2 causes multiple serious imbalances of severe acute respiratory syndrome as well as multiple organ dysfunctions including heart and kidney injury. Although the adverse impact of SARS-CoV-2 on pulmonary as well as cardiac systems have attracted remarkable attention, such impact on the renal system is still underestimated. Aim of the Study: The aim of this study was to evaluate the renal involvement among patients in a Covid-19 dedicated hospital. Methods: This was a prospective observational study which was conducted in the Department of Nephrology, Shaheed Suhrawardy Medical College, Dhaka, Bangladesh during the period from July 2020 to June 2021. This was a Covid-19 dedicated hospital during the pandemic situation of Covid-19. The study was approved by the ethical committee of the mentioned hospital. Proper written consents were taken from all the participants before data collection. In total 116 admitted patients in the mentioned hospital diagnosed for detecting renal involvement more than 15 year’s old were enrolled in this study as the study population. A predesigned questioner was used in data collection. Data were processed and analyzed by using MS Office and SPSS version 23 programs as per need. Results: In this study, in analyzing the mean ±SD serum creatinine levels of the participants, at baseline stage it was found as 2.24±1.49 where it was found as 3.06±2.18 at follow up stage. We did not find any significant correlation between the readings and the P value was found as 0.486. In electrolytes assessment, at baseline stage, the mean ±SD Na+, K+ and CI were found as 132.49±12.39, 4.34±0.75 and 97.28±10.09 mmol/L respectively. On the other hand, at follow up stage, those readings (Mean ±SD) were found as 138.30±15.07, 5.28±3.17 and 105.99±11.48 mmol/L respectively. In this study among ............

A young male who had history of ingestion of methanol developed severe anorexia, nausea, and profuse vomiting after a short period. After evaluation he was found to develop severe renal failure, metabolic acidosis & dyselectrolemia. He was given haemodialysis for several sessions. Few days later he developed weakness and blurred vision. Neurological evaluation showed toxic neuropathy. In spite of giving haemodialysis near about three months his renal function did not improved. Renal biopsy showed features suggestive of acute cortical necrosis. He was declared a case of End Stage Renal Disease (ESRD) & an arterio-venus fistula was created in his left forearm for maintenance of haemodialysis DOI: http://dx.doi.org/10.3329/bja.v11i1.20508 Bangladesh Journal of Anatomy, January 2013, Vol. 11 No. 1 pp 44-47