Study on Renal Involvement in Pandemic Covid-19: A Single Center Study in Bangladesh

Abstract

Background: Covid-19 imposes a serious public health pandemic affecting the whole world, as it is spreading exponentially. Besides its high infectivity, SARS-CoV-2 causes multiple serious imbalances of severe acute respiratory syndrome as well as multiple organ dysfunctions including heart and kidney injury. Although the adverse impact of SARS-CoV-2 on pulmonary as well as cardiac systems have attracted remarkable attention, such impact on the renal system is still underestimated. Aim of the Study: The aim of this study was to evaluate the renal involvement among patients in a Covid-19 dedicated hospital. Methods: This was a prospective observational study which was conducted in the Department of Nephrology, Shaheed Suhrawardy Medical College, Dhaka, Bangladesh during the period from July 2020 to June 2021. This was a Covid-19 dedicated hospital during the pandemic situation of Covid-19. The study was approved by the ethical committee of the mentioned hospital. Proper written consents were taken from all the participants before data collection. In total 116 admitted patients in the mentioned hospital diagnosed for detecting renal involvement more than 15 year’s old were enrolled in this study as the study population. A predesigned questioner was used in data collection. Data were processed and analyzed by using MS Office and SPSS version 23 programs as per need. Results: In this study, in analyzing the mean ±SD serum creatinine levels of the participants, at baseline stage it was found as 2.24±1.49 where it was found as 3.06±2.18 at follow up stage. We did not find any significant correlation between the readings and the P value was found as 0.486. In electrolytes assessment, at baseline stage, the mean ±SD Na+, K+ and CI were found as 132.49±12.39, 4.34±0.75 and 97.28±10.09 mmol/L respectively. On the other hand, at follow up stage, those readings (Mean ±SD) were found as 138.30±15.07, 5.28±3.17 and 105.99±11.48 mmol/L respectively. In this study among ............