This paper proposes a novel unified prediction approach for both small-signal and transient rotor angle stability as opposed to other studies that have only addressed transient rotor angle stability. Deep learning techniques are employed in this paper to train an online prediction model for rotor angle stability (RAS) using the voltage phasor measurements which are collected across the entire system. As a result, the trained model provides a fast yet accurate prediction of the transient stability status when a power system is subjected to a disturbance. Also, if the system is transiently stable, the prediction model updates the power system operator concerning the damping of low-frequency local and inter-area modes of oscillations. Therefore, the presented approach provides information concerning the transient stability and oscillatory dynamic response of the system such that proper control actions are taken. To achieve these objectives, advanced deep learning techniques are employed to train the online prediction model using a dataset which is generated through extensive time domain simulations for wide range of operating conditions. A convolutional neural network (CNN) transient stability classifier is trained to operate on the transient response of the phasor voltages across the entire system and provide a binary stability label. In tandem, a long-short term memory (LSTM) network is trained to learn the oscillatory response of a predicted stable system to capture the step-by-step dynamic evolution of the critical poorly damped low-frequency oscillations. The superior performance of the proposed model is tested using the New-England 10-machine, 39-bus, IEEE 16-machine, 68-bus, 5-area and IEEE 50-machine, 145-bus test systems and is verified with time domain simulation.

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Demand response (DR) programs have emerged as a potential key enabling ingredient in the context of smart grid (SG). Nevertheless, the rising concerns over privacy issues raised by customers subscribed to these programs constitute a major threat towards their effective deployment and utilization. This has driven extensive research to resolve the hindrance confronted, resulting in a number of methods being proposed for preserving customers' privacy. While these methods provide stringent privacy guarantees, only limited attention has been paid to their computational efficiency and performance quality. Under the paradigm of differential privacy, this paper initiates a systematic empirical study on quantifying the trade-off between privacy and optimality in centralized DR systems for maximizing cumulative customer utility. Aiming to elucidate the factors governing this trade-off, we analyze the cost of privacy in terms of the effect incurred on the objective value of the DR optimization problem when applying the employed privacy-preserving strategy based on Laplace mechanism. The theoretical results derived from the analysis are complemented with empirical findings, corroborated extensively by simulations on a 4-bus MG system with up to thousands of customers. By evaluating the impact of privacy, this pilot study serves DR practitioners when considering the social and economic implications of deploying privacy-preserving DR programs in practice. Moreover, it stimulates further research on exploring more efficient approaches with bounded performance guarantees for optimizing energy procurement of MGs without infringing the privacy of customers on demand side.

Since the declaration of SARS-CoV-2 outbreak as a pandemic, the United Arab Emirates (UAE) public health authorities have adopted strict measures to reduce transmission as early as March 2020. As a result of these measures, flight suspension, nationwide RT-PCR and surveillance of viral sequences were extensively implemented. This study aims to characterize the epidemiology, transmission pattern, and emergence of variants of concerns (VOCs) and variants of interests (VOIs) of SARS-CoV-2 in the UAE, followed by the investigation of mutations associated with hospitalized cases. A total of 1274 samples were collected and sequenced from all seven emirates between the period of 25 April 2020 to 15 February 2021. Phylogenetic analysis demonstrated multiple introductions of SARS-CoV-2 into the UAE in the early pandemic, followed by a local spread of root clades (A, B, B.1 and B.1.1). As the international flight resumed, the frequencies of VOCs surged indicating the January peak of positive cases. We observed that the hospitalized cases were significantly associated with the presence of B.1.1.7 (p < 0.001), B.1.351 (p < 0.001) and A.23.1 (p = 0.009). Deceased cases are more likely to occur in the presence of B.1.351 (p < 0.001) and A.23.1 (p = 0.022). Logistic and ridge regression showed that 51 mutations are significantly associated with hospitalized cases with the highest proportion originated from S and ORF1a genes (31% and 29% respectively). Our study provides an epidemiological insight of the emergence of VOCs and VOIs following the borders reopening and worldwide travels. It provides reassurance that hospitalization is markedly more associated with the presence of VOCs. This study can contribute to understand the global transmission of SARS-CoV-2 variants.

BackgroundGiven the current influx of 16S rRNA profiles of microbiota samples, it is conceivable that large amounts of them eventually are available for search, comparison and contextualization with respect to novel samples. This process facilitates the identification of similar compositional features in microbiota elsewhere and therefore can help to understand driving factors for microbial community assembly.ResultsWe present Visibiome, a microbiome search engine that can perform exhaustive, phylogeny based similarity search and contextualization of user-provided samples against a comprehensive dataset of 16S rRNA profiles environments, while tackling several computational challenges. In order to scale to high demands, we developed a distributed system that combines web framework technology, task queueing and scheduling, cloud computing and a dedicated database server. To further ensure speed and efficiency, we have deployed Nearest Neighbor search algorithms, capable of sublinear searches in high-dimensional metric spaces in combination with an optimized Earth Mover Distance based implementation of weighted UniFrac. The search also incorporates pairwise (adaptive) rarefaction and optionally, 16S rRNA copy number correction. The result of a query microbiome sample is the contextualization against a comprehensive database of microbiome samples from a diverse range of environments, visualized through a rich set of interactive figures and diagrams, including barchart-based compositional comparisons and ranking of the closest matches in the database.ConclusionsVisibiome is a convenient, scalable and efficient framework to search microbiomes against a comprehensive database of environmental samples. The search engine leverages a popular but computationally expensive, phylogeny based distance metric, while providing numerous advantages over the current state of the art tool.Electronic supplementary materialThe online version of this article (doi:10.1186/s12859-017-1763-0) contains supplementary material, which is available to authorized users.

IntroductionA rapid increase in COVID-19 cases due to the spread of the Delta and Omicron variants in vaccinated populations has raised concerns about the hospitalization risk associated with, and the effectiveness of, COVID-19 vaccines.MethodThis case–control study aims to determine the hospitalization risk associated with the inactivated BBIBP-CorV (Sinopharm) and mRNA BNT162b2 (Pfizer–BionTech) vaccines, and their effectiveness reducing the rate of hospital admission between 28 May 2021 and 13 January 2022, during the Delta and Omicron outbreaks. The estimation of vaccine effectiveness of 4,618 samples was based on the number of patients hospitalized at different vaccination statuses, adjusted for confounding variables.ResultsHospitalization risk increases in patients affected with the Omicron variant if patients are aged ≤ 18 years (OR 6.41, 95% CI 2.90 to 14.17; p &lt; 0.001), and in patients affected with the Delta variant if they are aged &gt; 45 years (OR 3.41, 95% CI 2.21 to 5.50; p &lt; 0.001). Vaccine effectiveness reducing the rate of hospital admission for fully vaccinated participants infected with the Delta and Omicron variants was similar for both the BBIBP-CorV (94%, 95% CI 90% to 97%; 90%, 95% CI 74% to 96%) and BNT162b2 vaccines (95%, 95% CI 61% to 99.3%; 94%, 95% CI 53% to 99%), respectively.DiscussionThe BBIBP-CorV and BNT162b2 vaccines utilized in the UAE vaccination program were highly effective in reducing the rate of COVID-19-related hospitalization during the Delta and Omicron outbreaks, and further effort must be taken to achieve high vaccine coverage rates in children and adolescents in the global context to reduce the hospitalization risk associated with COVID-19 on an international scale.

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The Internet-of-Things (IoT) has engendered a new paradigm of integrated sensing and actuation systems for intelligent monitoring and control of smart homes and buildings. One viable manifestation is that of IoT-empowered smart lighting systems, which rely on the interplay between smart light bulbs (equipped with controllable LED devices and wireless connectivity) and mobile sensors (possibly embedded in users’ wearable devices such as smart watches, spectacles, and gadgets) to provide automated illuminance control functions tailored to users’ preferences (e.g., of brightness, color intensity, or color temperature). Typically, practical deployment of these systems precludes the adoption of sophisticated but costly location-aware sensors capable of accurately mapping out the details of a dynamic operational environment. Instead, cheap oblivious mobile sensors are often utilized, which are plagued with uncertainty in their relative locations to sensors and light bulbs. The imposed volatility, in turn, impedes the design of effective smart lighting systems for uncertain indoor environments with multiple sensors and light bulbs. With this in view, the present article sheds light on the adaptive control algorithms and modeling of such systems. First, a general model formulation of an oblivious multisensor illuminance control problem is proposed, yielding a robust framework agnostic to a dynamic surrounding environment and time-varying background light sources. Under this model, we devise efficient algorithms inducing continuous adaptive lighting control that minimizes energy consumption of light bulbs while meeting users’ preferences. The algorithms are then studied under extensive empirical evaluations in a proof-of-concept smart lighting testbed featuring LIFX programmable bulbs and smartphones (deployed as light sensing units). Lastly, we conclude by discussing the potential improvements in hardware development and highlighting promising directions for future work.