At the current stage of the economy development the efficient control of the enterprise activity based on the anticipatory adaptation to continuous changes of the environment in tune with the trend of the internal medium dynamic self-organization is the most important prerequisite of the success, so the issues of scientifically substantiated control of changes become especially urgent. The authors have substantiated the essence and comprehensive nature of the process of business changes, and its predominantly innovative character has been determined. The algorithm of controlling business changes at the enterprise based on graph theory methodology has been suggested based on identification of the communication basis of business processes. Using the algorithm enables making scientifically substantiated decisions facilitating achievement of the enterprise functioning goals at some period of time. Based on the algorithm, the authors have developed methodology for optimization of innovation-based organizational enterprise management structure implemented in business practice of RZhDstroi JSC Holding. The results of the suggested methodological tooling validation have shown the appropriateness of the tools in the enterprise business activity.
Nowadays there are certain difficulties in the early diagnosis of ulcerative colitis, proceeding with minimal intestinal symptoms. The etiology of the disease remains unclear to this day; there is no exact information about the prevalence of the disease due to the large number of latent forms and the low number of patients seeking medical help. This article presents the results of a retrospective analysis of the incidence of ulcerative colitis in the coloproctology department of the First Republic Clinical Hospital of Izhevsk. The study was conducted to assess the frequency of occurrence and determine the internal picture of ulcerative colitis. To achieve this goal, we selected 34 patients with ulcerative colitis. A statistical study was conducted on the following criteria: gender composition, age groups, forms of the disease, localization, complications, and main complaints. The length of hospital stay often was not more than 20 days. The literature on this pathology was also studied and presented in the form of a theoretical basis, which consisted of the determination and etiology of inflammatory bowel diseases. Due to the unknown etiology, insufficiently studied pathogenesis, difficult differential diagnosis with other intestinal diseases and insufficiently perfect treatment methods, there are a large number of unresolved problems in the field of ulcerative colitis. That is why, in this article we tried to reveal the problem of the features of the course and complex therapy of that disease in clinical practice.
The article discusses the urgent problems of the educational process in higher education caused by crisis phenomena in pedagogy as the main way of personality development.One of the ways to overcome the crisis is the formation of the worldview of the teacher, substantiates the content of his intellectual, cognitive, communication, research competencies.
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