Today, the synthesis of biocompatible and bioresorbable composite materials such as “polymer matrix-mineral constituent,” which stimulate the natural growth of living tissues and the restoration of damaged parts of the body, is one of the challenging problems in regenerative medicine. In this study, composite films of bioresorbable polymers of polyvinylpyrrolidone (PVP) and sodium alginate (SA) with hydroxyapatite (HA) were obtained. HA was introduced by two different methods. In one of them, it was synthesized in situ in a solution of polymer mixture, and in another one, it was added ex situ. Phase composition, microstructure, swelling properties and biocompatibility of films were investigated. The crosslinked composite PVP-SA-HA films exhibit hydrogel swelling characteristics, increasing three times in mass after immersion in a saline solution. It was found that composite PVP-SA-HA hydrogel films containing HA synthesized in situ exhibited acute cytotoxicity, associated with the presence of HA synthesis reaction byproducts—ammonia and ammonium nitrate. On the other hand, the films with HA added ex situ promoted the viability of dental pulp stem cells compared to the films containing only a polymer PVP-SA blend. The developed composite hydrogel films are recommended for such applications, such as membranes in osteoplastic surgery and wound dressing.
Rhenium I 7000Octahedral Hexahydroxo Rhenium Cluster Complexes [Re 6 Q 8 (OH) 6 ] 4-(Q: S, Se): Synthesis, Structure, and Properties. -The structures of the new rhenium cluster compounds (III) (triclinic, space group P1, Z = 1) and (Vb) (monoclinic, P21/n, Z = 2) are determined by single crystal XRD. Compounds (III) exhibit luminescent properties. -(YAROVOI, S. S.; MIRONOV, Y. V.; NAUMOV, D. Y.; GATILOV, Y. V.; KOZLOVA, S. G.; KIM, S.-J.; FEDOROV*, V. E.; Eur.
Rhenium I 7000First Examples of Chalcofluoride Rhenium Cluster Complexes with Cubane-Like Anions [Re4Q4F12] 4-(Q: S, Se). -The new compounds (III) are the first examples of cubane like clusters with fluoride ligands in the outer sphere of a cluster core {Re4Q4}. (IIIa) crystallizes in the trigonal space group R3 with Z = 24 and (IIIb) in the triclinic space group P1 with Z = 4 (single crystal XRD). The hydrophilic terminal fluoride ligands of the cluster anions are included in the hydrogen bonding system of their hydrate shells. -(MIRONOV, Y. V.; YAROVOI, S. S.; NAUMOV, D. Y.; KURATIEVA, N. V.; KOZLOVA, S. G.; SIMON, A.; FEDOROV*, V. E.; Eur.
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