Prevalensi diabetes melitus berdasarkan hasil riset kesehatan dasar (Riskesdas, 2013) tertinggi di Indonesia terdapat di provinsi DI Yogyakarta. Diabetes melitus merupakan penyakit kronis yang membutuhkan pengobatan jangka panjang dan kompleks dimana salah satu penentu keberhasilan terapi bergantung pada kepatuhan penggunaan obat. Tujuan penelitian ini untuk mengetahui gambaran karakteristik pasien meliputi jenis kelamin, usia, tingkat pendidikan, durasi penyakit, komorbid, dan penggunaan ADO terhadap kepatuhan pasien diabetes melitus tipe 2. Penelitian ini menggunakan metode observasional dengan rancangan analisis potong lintang yang dilakukan secara retrospektif terhadap 123 pasien diabetes melitus tipe 2 rawat jalan di puskesmas daerah Yogyakarta pada bulan Agustus-September tahun 2015. Metode pengambilan sampel menggunakan teknik accidental sampling. Instrumen penelitian berupa lembar pengambilan data dan kuesioner Morisky Medication Adherence MMAS-8. Data dianalisis menggunakan Chi-Square. Hasil penelitian menunjukkan bahwa secara keseluruhan tingkat kepatuhan pasien diabetes melitus tipe 2 berada pada tingkat kepatuhan rendah. Hubungan antara pengaruh karakteristik pasien: jenis kelamin (p=0,275), usia (p=0,473), tingkat pendidikan (p=0,157), durasi penyakit (p=0,097), jumlah komorbid (p=0,79), dan ADO (p=0,401) terhadap tingkat kepatuhan tidak signifikan (p>0,05). Kata kunci: Diabetes melitus tipe 2, karakteristik pasien, kepatuhan
The increasing prevalence of diabetes mellitus (DM) in Indonesia requires participation of all parties including pharmacists. This study aims to determine the impact of the implementation of home pharmacy service guidelines for patients with type 2 diabetes mellitus on the level of knowledge, medication adherence, therapeurical satisfaction and glycemic control. This study used a quasi-experimental design with one group pre-test and post-test design involving 37 patients with type 2 diabetes mellitus who met the requirements of inclusion and exclusion criterias. The Diabetes Knowledge Questionnaire (DKQ-24) and the Diabetes Medication Satisfaction Tool (DMSAT) were used for collecting the data. Patient adherence was measured using a pillcount method and fasting blood sugar levels (FSB) data were obtained from the laboratory results. The study was conducted in two community health centers and patient’s home in the Yogyakarta Municipality area. The data were analysed using Wilcoxon and Spearman test. The results showed the change of the level of knowledge, medication adherence, therapeutic satisfaction and glycemic control before and after intervention of pharmacy services at home. The average decreasing of fasting blood sugar levels 17.09 mg/dL ± 1.43
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