Rasa Shastra basically deals with the pharmaceutics of drugs of mineral and metallic origin. In Rasa Shastra Kupipakwa Rasayana holds an unique importance as compared to other formulations due to its miraculous effects on dreadful and chronic ailments, with rapid action. Kupipakwa Rasayana are well known to be potent because of specific pharmaceutical process, excellent clinical result, long lasting potency and safety even on prolonged use. The Kupipakwa Rasayanas are prepared in especially prepared glass bottle, called as Kupi, by adopting a specially designed instrument, known as Valuka Yantra. Haragouri Rasa is a sublimated mercurial preparation known for its use in different types of Vata-Vyadhi, Rasayana, Vajikarana. Now a days people are more suffering from different types of Vatavyadhi due to different kinds of lifestyle, food habits etc.

Background: Streevandhyatva or Female Infertility is a Gynaecological disorder. The etiological factors include the defect in the immature Sperm and Ovum during the fertile period. Incidence rate according to W.H.O is 20-30% is primary while 70-80% of cases are secondary Infertility. Now a day’s maximum number of Female Infertility is due to sedentary lifestyle, Psychological factors, Nutritional deficiency and Stress leads to different condition like PCOD, Obesity, Irregular Menstrual cycle and anovulatory cycle etc. The present study was carried out as a pilot study on 10 subjects of female infertility with the use of Phalagruta Uttarabasti followed by Prakshalana and Pichudharana. Three to five consecutive cycles of Phalagruta Uttarabasti was administered, Posology - Uttarabasti with Phalagruta 5ml daily for 3 days. Diagnostic criteria - Patients are diagnosed based on signs and symptoms like anovulation, PCOD etc., before and after treatment with USG. Results - Among 10 patients, 4 patients - Well response, 2 patients - Improved with follicular study, 3 patients - Poor responded, 1 Patient discontinued the study.