The potential exposure to bisphenol A (BPA) from the use of consumer products or packages made from bisphenol A-derived polycarbonate resins was calculated. The calculation was made on the basis of migration data from moulded discs prepared from a composite of polycarbonate resins. The data were obtained using the customary experimental procedures developed by the United States Food and Drug Administration (FDA). The potential migration of BPA to food from its contact with articles made from polycarbonate resins was determined using food-simulating solvents and time and temperature conditions recommended by FDA. The study demonstrates that no detectable BPA was found in the extracts obtained under FDA's most severe default testing condition using a method sensitive to 5 parts per billion (ppb) in the food simulants. Using these data, along with FDA's conventional procedure for estimating potential dietary exposure using food simulating migration data, the potential dietary exposure to bisphenol A from use of polycarbonate resins was determined to be less than 0.25 ppb.
The potential exposure to p-nonylphenol from the use of tris(nonylphenyl)phosphite (TNPP) in food-contact materials was calculated. The calculation was made on the basis of migration data from moulded plaques prepared from linear low-density polyethylene (LLDPE), films prepared from LLDPE and polyvinyl chloride (PVC) films. The data were obtained using the customary expermental procedures developed by the US Food and Drug Administration (FDA). The potential migration of p-nonylphenol to food from the use of TNPP as a component of food-contact articles was determined using food-simulating solvents and time and temperature conditions recommended by the FDA. Using the data obtained from these studies, along with procedures based on the FDA's conventional method for estimating potential dietary exposure using food simulating migration data, the potential dietary exposure to p-nonylphenol from the use of TNPP was determined to be approximately 25.5 parts per billion (ppb). Because the conditions of the migration tests exaggerate actual use conditions, this value overstates the potential dietary exposure.
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