At time points where the variance of the random effect was estimated equal to 0, we fit a fixed-effects model using the genotype only. Finally, within each time point, we performed the post hoc pairwise comparisons among the 3 different genotypes using the emmeans R package, and we corrected for multiple testing using Tukey's adjustment method.Study approval. All experiments using laboratory mice were performed in accordance with the NIH Guide for the Care and Use of Laboratory Animals
The data suggest that high strains are not requisite for bone remodeling. How the lingual symphysis negotiates a high strain environment without the reparative benefit of remodeling is yet to be elucidated, but the data prompt reevaluation of the relationship of targeted remodeling to stress histories. Differences in osteonal bone density between taxa might reflect feeding or dietary influences on remodeling activity, but sample composition prevents parsing behavioral from other taxon-specific effects.
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