COVID-19 is considered as a major public health problem caused by the SARS CoV-2. This Viral infection is known to induce worldwide pandemic in short period of time. Emerging evidence suggested that the transmission control and drug therapy may influence the preventive measures extensively as the host surrounding environment and pathogenic mechanism may contribute to the pandemic condition earlier in COVID-19 disease. Although, several animals identified as reservoir to date, however human-to-human transmission is well documented. Human beings are sustaining the virus in the communities and act as an amplifier of the virus. Human activities i.e., living with the patient, touching patient waste etc. in the surrounding of active patients or asymptomatic persons cause significant risk factors for transmission. On the other hand, drug target and mechanism to destroy the virus or virus inhibition is depends on diversified approaches of drugs and different target for virus life cycle. This article describes the sustainable chemical preventive models understanding, requirements, technology adaptation and the implementation strategies in these pandemic-like situations. As the outbreak progresses, healthcare models focused on transmission control through disinfections and sanitization based on risk calculations. Identification of the most suitable target of drugs and regional control model of transmission are of high priority. In the early stages of an outbreak, availability of epidemiological information is important to encourage preventive measures efforts by public health authorities and provide robust evidence to guide interventions. Here, we have discussed the level of adaptations in technology that research professionals display toward their public health preventive models. We should compile a representative data set of adaptations that humans can consider for transmission control and adopt for viruses and their hosts. Overall, there are many aspects of the chemical science and technology in virus preventive measures. Herein, the most recent advances in this context are discussed, and the possible reasons behind the sustainable preventive model are presented. This kind of sustainable preventive model having adaptation and implementation with green chemistry system will reduce the shedding of the virus into the community by eco-friendly methods, and thus the risk of transmission and infection progression can be mitigated.

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: Annually about 2 million people suffer from various modes of burn injuries worldwide of whom more than a lakh die. In India about 60,000 people suffer from burns annually, more than 50,000 are treated in hospitals and about 10,000 succumb to thermal injury. : The primary importance of present study is to have a better understanding of changes occurring in this vital organ in relation to survival period of burn victims, to emphasis that hepatic dysfunction is also an important determinant to survival of burn victims. : Forensic Medicine and Toxicology Department of a tertiary care hospital. A descriptive study was performed on 37 burn deceased of both the sexes of different age groups brought into the mortuary of the Department of Forensic Medicine during the period of July 2009 to December 2010. Liver specimens were collected and the H& E stained slides studied separately by two independent observers. Fatty infiltrations in the liver were present at various stages i.e. microvesicular steatosis to macrovesicular steatosis, followed by fatty cyst in victims with survival periods ranging from 2 days to 30 days. Thus as the survival period increased, the proportion of involvement of the hepatic lobule increased with focal / confluent centrilobular hepatocyte necrosis in 54.5% victims of 8-15 days survival and ultimately ended into massive hepatocyte necrosis leading to complete loss of lobular architecture in victims who survived for 16- 30 days. : The present study indicates that liver damage in the form of hepatic steatosis leading to hepatocyte necrosis and latter complete loss of liver architecture and consecutively hepatic dysfunction occurs with increasing survival period of burn victims therefore, maintenance of Liver integrity and function are crucial for post burn survival.