Lens opacities may affect the image quality of OCT scans used to measure RNFL thickness as indicated by preoperative low SNR. Cataract extraction results in an apparent increase of the RNFL thickness.
The awareness of the nature of COAG in this population was low and incidence of perceived drug related systemic symptoms very high. Both of these may contribute to poor compliance.
PURPOSE
To evaluate the repeatability and inter-operator reproducibility of the Pascal dynamic contour tonometry (DCT), Ocular Response Analyzer (ORA) and Goldmann applanation tonometer(GAT) in a single population of normal subjects.
METHODS
The study included fifty-two eyes from 26 normal subjects. One operator measured the intraocular pressure (IOP) with each tonometer three times while two additional operators each measured the IOP with each tonometer once. Repeatability and reproducibility were assessed by the coefficient of Variation (CV) and Intraclass Correlation Coefficient (ICC). Agreement among tonometers was also assessed using Bland-Altman plots.
RESULTS
The mean age of included subjects was 31.5 ±8.8 years and 15 (58%) were female. In general, both intra-operator repeatability and inter-operator reproducibility were significantly higher for DCT compared to the other tonometers. Intra-operator DCT (CV = 3.7, ICC = 0.89), GAT (CV = 9.7, ICC = 0.79), IOPg (CV = 7.0, ICC = 0.79) and IOPcc (CV = 9.8, ICC = 0.57). Inter-operator DCT (CV=6.1, ICC = 0.73), GAT (CV=9.0, ICC=0.82) and IOPg (CV=10.8, ICC = 0.63), IOPcc (CV=11.7, ICC = 0.49)
CONCLUSION
Overall, DCT was significantly more repeatable and reproducible than GAT, IOPg and IOPcc. The better reproducibility of the DCT may result in more precise measurements for monitoring intraocular pressure changes over time compared to GAT and ORA.
Several vascular factors, including systemic hypertension (or high blood pressure [HBP]), ocular perfusion pressure, and nocturnal hypotension, have been identified as risk factors for the development and progression of glaucoma. The results of epidemiologic studies of these factors and their relationships to intraocular pressure (IOP) and open-angle glaucoma (OAG) have been contradictory. Inconsistent definitions of HBP and OAG, inconsistent design, and differing population characteristics within these studies have obfuscated definitive conclusions. Here, we review the relationships among blood pressure, IOP, and OAG.
Purpose To examine the reasons for and outcomes of the scleral explant removal over the last decade. Methods A case note review of patients undergoing scleral explant removal in the operating theatre over a period of 10 years from January 1990 to December 1999. The following information was retrieved: age, sex, reason for explant removal, duration of explant (ie interval between primary surgery and explant removal), type of explant, symptomatic relief, preoperative and postoperative retinal status including redetachment, causes for redetachment, and follow-up. Mann-Whitney U-test and Fisher's exact test were used for statistical analysis. Results A total of 72 patients were eligible for the study. The average age was 54.1717.0 years (range, 17-84 years). The mean duration of explant was 50.1 years (range, 1-282 months) and mean follow-up was 18.3 months (range, 4-120 months). In all, 51 (70.8%) patients had a sponge silicone explant, 13 (18%) patients had a solid silicone explant, whereas eight (11.1%) patients had a combination of the two. The commonest reason for the explant removal was extrusion (n ¼ 34, 47.2%) closely followed by pain (n ¼ 29, 40.2%). Symptomatic relief was achieved in 88% of patients. Six patients (8.3%) suffered retinal redetachment post explant removal. There was no statistically significant correlation between the reason for the removal or the duration of the explant and retinal redetachment. The majority (N ¼ 5) of redetachment occurred within 6 months of the explant removal (Po0.01). Conclusion The Scleral explant removal provides symptomatic relief to the majority of patients, but is associated with a small risk of redetachment especially within 6 months postoperatively.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.