Lens opacities may affect the image quality of OCT scans used to measure RNFL thickness as indicated by preoperative low SNR. Cataract extraction results in an apparent increase of the RNFL thickness.
The reduction in the VAS pain score with the conjunctival mould was statistically significant (p<0.01). The surgeons found that the device, which was easy to insert, offered excellent globe stability and a safe, reproducible entry site and angle of needle insertion.
Orbital cellulitis following sub-Tenon's anaesthesia H Dahlmann et al
200Eye TGF-, which are known to induce expression of ␣E7 on IELs. 9 This may be another reason why IELs are present throughout all the layers of the dysplastic epithelium but only along the basal cells of normal conjunctival epithelium.We did not notice any definite relationship between the degree of dysplasia and E-cadherin expression. These findings contrast to observations made with cervical intraepithelial neoplasia where reduced Ecadherin expression related to an increasing loss of cell differentiation. 10 The observations made in this study with regard to E-cadherin suggest that the distribution of IELs in normal conjunctiva and CIN cannot be explained by the distribution of E-cadherin alone.
A 37-year-old man presented to the emergency department with a visor impacted in the left orbit after a motorbike accident. His initial injury appeared to be limited to the orbit. Because the bleeding appeared disproportionate to the orbital injury, an intracranial injury was suspected. Subsequently, on hemicraniotomy, the tip of the visor was found at the bifurcation of the internal carotid artery. The avulsed upper eyelid was found under the frontal lobe. The patient underwent the clipping of internal carotid artery and middle and anterior cerebral artery with replantation of the upper eyelid. Neurologic damage was limited to loss of vision, right foot drop, and bowel and bladder incontinence. This case of penetrating orbital trauma demonstrates that the absence of focal neurologic deficit and radiologic signs suggestive of intracranial injury may not rule out life-threatening intracranial injury.
Aim To identify the relative incidence and profile of adverse drug reaction (ADR) to various topical ocular hypotensives in a hospital setting. Methods All the patients presenting in outpatients clinic and accident and emergency with an ADR to topical hypotensive agent from August 2000 to January 2001 were included in the study. Details regarding the type date of commencing the treatment, the date of developing ADR, time to resolution of the ADR were noted. Results Over the period of 6 months, 66 patients presented with 73 ADRs. Brimonidine was the most frequent offending agent. In total, 23 (34.8%) presented with ADR after being commenced on treatment for more than 12 months. In all, 16 (24%) patients had IOP421 on presentation, eight (12%) patients underwent filtration surgery following the development of ADR. Conclusion Adverse drug reaction to ocular hypotensive agents is not uncommon and can have a major impact on glaucoma management. Delayed presentation and association with raised intraocular pressure presentation emphasise the need for effective patient education to encourage prompt reporting of ADR.
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