TUDCA promote the chondrogenic properties of osteoarthritic chondrocytes at submicellar concentrations by reducing the intracellular cholesterol and increasing membrane fluidity.

Supporting Information. The Supporting Information is available free of charge on the ACS Publications website at DOI: The SEM and TEM images of well dispersed HA/SWCNT solutions with 7 mg/mL SWCNTs; Chemical modification sites in HA and the schematic representations of HA crosslinked with HMDA after activation using EDC and HOBt; FTIR spectra of SWCNTs, uncrosslinked and crosslinked HA/SWCNT microfibers; 3D topography of uncrosslinked and crosslinked HA/CNTs microfiebrs with 7 mg/mL SWCNT concentration obtained using AFM; Tensile strength of uncrosslinked and crosslinked swollen HA/SWCNT microfibers as a function of SWCNT concentration; Failure strain of uncrosslinked and crosslinked swollen HA/SWCNT microfibers as a function of SWCNT concentration; SEM images of well dispersed HA/SWCNT solutions with 4 mg/mL and 7 mg/mL SWCNTs; Micrographs and SEM of HA/SWCNT dispersion with different SWCNT concentrations; Schematic illustration of the HA/SWCNT microfibers on the paper frame with different bending angles; Schematic illustration of the specimen (bottom), photographs of the fibers being tested in a tensile tester at rest (left) and maximum strain (right), and the corresponding load-displacement curve (middle); Cyclic voltammetry outcome of the HA/SWCNT microfibers with 7 mg/mL SWCNT concentration: current vs. scan rate; Viability of NIH-3T3 fibroblasts after five days of culture on the surface of HA/SWCNT microfibers with 7 mg/mL SWCNT concentration; The authors declare no competing financial interest.

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