COVID-19 (corona virus disease 2019) is a global public health emergency caused by a new corona virus with severe acute respiratory syndromelike characteristics (SARS-CoV-2). We aimed to evaluate whether gender and age are major risk factors for SARS-CoV-2 infection. For the study, 300 positive cases diagnosed during the period of July 2020 to September 2020 were included. Results showed that 69% of study samples were male of which 84% were in the >51 years old age group. And 31% of study samples were female of which 63% were in the 4-19 years old age group. ANOVAresults indicated that the means of Ct values varied signicantly between age groups (F=2.703; p-value= 0.045). The lower Ct values were recorded in males (29.01±4.35) in comparison to females (29.84±3.98) while, the difference between the means of the two groups was not signicant. Our study concluded that males have higher viral load than females and for both sexes, age was found to be a signicant risk factor for severity of COVID-19.
Background: The ongoing novel coronavirus (COVID-19) pandemic is shaping the world on an unprecedented scale affecting more than 10.3 million individuals across the globe . Various studies have found that C- reactive protein (CRP ) levels could reflect disease severity and should be used as a key indicator for disease monitoring . Objective: To assess the level of C reactive protein(CRP) in initial stage of COVID-19 cases and its correla-tion with clinical presentation of disease. Materials and method:This retrospective case-control study includes 60 RT- PCR (reverse tran-scriptase-polymerase chain reaction) confirmed positive cases above the age of 18 years who were subsequently admitted between May- June, 2020, at Mahendra Mohan Choudhury Hospi-tal(MMCH) –an annexe hospital of Gauhati Medical College and Hospital(GMCH), Kamrup, As-sam. Result:The mean CRP value in the case group was 6 ± 2.36 mg/L while in control group it was 3.03 ± 1.20 which was found to be significantly raised (p<0.005) Conclusion: CRP may be an important index for prognosis and assessment of early stage of COVID-19. CRP levels can also be used in the treatment and management of positive cases.
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