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A methodology based on a loss analysis procedure has been presented to predict the performance of centrifugal slurry pumps handling solid-liquid mixtures. Various energy-head losses in the pump have been estimated using analytical models based on the pump geometry and the properties of suspended solids. The proposed methodology accounts for the constructional differences of the slurry pump as compared with the conventional pump. The predicted values of head over the operating range of flowrates of the pump have been found to be in reasonable agreement with the measurements made at various rotational speeds and solid concentrations.

AbstractPresent study was planned to investigate the efficacy of SLBSP vs. standardized BSE for symptomatic knee osteoarthritis (OA) treatment. It was prospective, randomized, double-blind, double-dummy, placebo-controlled, and single-centre clinical trial for symptomatic osteoarthritis of knee. Subjects were randomized to receive SLBSP capsule + BSE Placebo or BSE tablet + SLBSP placebo for two months. Patients were allowed to take rescue analgesics (Acelofenac 100 mg). Improvement in pain and function was assessed utilizing WOMAC, VAS. Level of CTX-II in urine and serum levels of inflammatory cytokines including IL-2, IL-4, IL-6, TNF-α, and IFN-γ were measured initially and at end of treatment. WOMAC and VAS score improved markedly in SLBSP as well as in BSE arm (p < 0.05). Difference in VAS and WOMAC scores between the two arms was not statistically significant. Most significant effect was observed in the need for rescue analgesics. SLBSP caused marked lowering of pro-inflammatory cytokines levels whereas a several fold increase was noted in the BSE arm (p < 0.05). Both groups showed marked improvement in pain, SLBSP being superior to BSE with respect to reducing the need for rescue analgesics in addition to modulating inflammatory cytokines.