Seri (Muntungia calabura L) leaves have various secondary metabolite components and it is necessary to carry out phytochemical screening and determination of their levels as well as in vitro testing of their bioactivity as antioxidants and antibacterials. Extraction was carried out by maceration method with ethanol as solvent. Determination of phenol with Folin-Ciaocalteu reagent was measured at a wavelength of 765 nm, while the levels of flavonoids with AlCl3 reagent were measured at a wavelength of 431 nm using the colorimetric method, antioxidant activity testing with 2,2-diphenyl-1-picrylhydrazyl (DPPH) was measured at a wavelength 517 nm using UV-Vis spectrophotometry, and antibacterial activity testing was carried out on the bacteria Ercherichia coli, Staphylococcus aureus, and Staphylacoccus epidermidis using the disc paper diffusion method with various concentrations of 12.5%, 25%, 50%,75%, DMSO10% for control negative and Chlororamphenicol as a positive control by observing the clear zone in mm. Phenolic content equivalent to 2.258±0.008 mg gallic acid (mg GAE/g dw), flavonoid content 2.476±0.019 mg equivalent to quercetin (mg QE/g dw), antioxidant activity of ethanol extract of M. calabura L. leaves, leaves was 19.004, antibacterial activity against Ercherichia coli, Staphylococcus aureus, and Staphylacoccus epidermidis with a strong category. The ethanol extract of the of Seri (Muntingia calabura, L) leaves contains flavonoids, phenolics and shows activity as an antioxidant with a very strong category and a strong antibacterial category
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.