Diabetes Mellitus - Hipertensi (DM-HT) adalah intoleransi karbohidrat yang ditandai dengan resistensi insulin, defisiensi insulin relatif, produksi glukosa berlebih oleh hati dan hiperglikemia. Diabetes dan komplikasinya membawa kerugian besar bagi penderita diabetes dan keluarga. Upaya yang dilakukan untuk mengendalikannya adalah dengan latihan prolanis. Tujuan penelitian ini untuk mengetahui pengaruh senam prolanis terhadap tekanan darah dan pengendalian kadar glukosa darah pada pasien DM Tipe II dan Hipertensi di Puskesmas Aek Habil Sibolga. Jenis penelitian dengan menggunakan one group pre and post test dimana penelitiannya terdapat pretest sebelum diberi perlakuan dan posttest setelah diberi perlakuan. Populasi dalam penelitian ini adalah seluruh penderita diabetes tipe II dan hipertensi di wilayah kerja Puskesmas Aek Habil dengan jumlah sampel sebanyak 49 orang yang diambil dengan teknik purposive sampling. Analisis data menggunakan Paired t-test. Sebelum dianalisis dilakukan uji normalitas data terlebih dahulu dimana diperoleh hasil untuk data kadar gula darah terdistribusi normal dan untuk data tekanan darah sistol dan diastol tidak berdistribusi normal. Berdasarkan hasil penelitian terdapat pengaruh senam prolanis terhadap gula darah dengan signifikansi 0,001. Pada tekanan darah didapatkan hasil ada pengaruh senam prolanis terhadap perubahan tekanan darah sistol dengan signifikansi 0,000, dan tekanan darah diastol dengan signifikansi 0,00. Dari hasil penelitian dapat disimpulkan bahwa terdapat pengaruh Senam Prolanis terhadap pengendalian kadar gula darah dan tekanan darah pada penderita Diabetes Mellitus dan Hipertensi. Diharapkan kepada tenaga kesehatan dapat meningkatkan upaya penanganan penyakit diabetes melitus dengan mengoptimalkan kegiatan senam prolanis.

Pendahuluan; anak-anak usia 6-12 tahun rentan mengalami peralihan usia, karena peralihan usia gigi dengan gigi permanen. Tujuan; mengetahui tingkat pengetahuan dan perilaku kesehatan gigi dan aral pada siswa SD kelas 5 dan 6 yang memiliki klinik kesehatan gigi dan belum memiliki klinik kesehatan gigi. Metode; merupakan penelitian survei analitik dengan desain cross sectional. Uji analisis menggunakan chi square. Hasil; menunjukkan tingkat pengetahuan kesehatan gigi dan mulut siswa SD kelas 5 dan 6 yang tidak memiliki klinik gigi mendapatkan nilai p = 0,023. Perbedaan perilaku menjaga kesehatan gigi dan mulut pada siswa SD kelas 5 dan 6 yang tidak memiliki klinik kesehatan gigi adalah p=0,006. Kesimpulan; bahwa terdapat perbedaan tingkat pengetahuan dan perilaku kesehatan gigi dan mulut antara siswa kelas 5 dan 6 SD yang memiliki klinik kesehatan gigi dengan yang tidak memiliki klinik kesehatan gigi.

The aim of this study was to assess the clinical efficacy of new mouthwash based on kapulaga fruit (Amomum cardamommum L.) containing 0.5% essential oil and compared to 0.5% Listerine Ⓡ as a positive control and placebo in reducing volatile sulphur compounds (VSCs) concentration of halitosis subjects. Methods: A randomized, double blinded, cross-over design was conducted among 20 healthy volunteers in Medan, Indonesia. Subjects were divided into 3 groups (Cardamom, Listerine Ⓡ , placebo group) and instructed to rinse 10 ml of experiment and control mouthwash twice per day for 5 days. After one week washout periods, each group used the opposite mouthwash. The concentration of VSCs, hydrogen sulfide, methyl mercaptan, and dimethyl sulfide were assessed twice daily for 5 days (morning at 5 a.m. and afternoon at 11 a.m.) by using oral chroma and organoleptic measurement. The three mouthwash were analyzed statistically by repeated measures ANOVA. Results: Either Cardamom or Listerine Ⓡ was effective in reducing VSCs for up to 4 to 5 hours after mouth rinsing, while placebo not. An analysis showed significant differences of cardamom essential oil in mouthwash and positive control group (p<0.05) from 1st and 5th day while no significant difference in placebo group (p>0.05). Results showed that Cardamom more effective than the other two mouthwashes. Unlike other mouthwash in general, the advantage of cardamom essential oil in mouthwash is alcohol-free, that could avoid from oral pain and sensitivity. Conclusion: It can be concluded that 0.5% cardamom containing essential oil in mouthwash is useful to overcome halitosis.

Latar Belakang: Gingivitis pada saat kehamilan disebabkan oleh peningkatan konsentrasi hormon estrogen dan progesteron. Keadaan ini ditandai dengan papila interdental yang memerah, bengkak, mudah berdarah disertai rasa sakit menyebabkan gingiva menjadi sensitif khususnya terhadap toksin maupun iritan seperti plak dan kalkulus yang mengakibatkan gingiva mengalami peradangan. Tujuan: Untuk melihat hubungan antara tingkat kebersihan dengan tingkat keparahan gingivitis terhadap wanita hamil. Metode: Sebanyak 32 wanita hamil di RSUD DR. RM. Djoelham Binjai dibagi menjadi 2 kelompok, yaitu 16 orang trimester kedua dan 16 orang trimester ketiga dilakukan pemeriksaan status OHI-S dan gingivitis dengan menggunakan indeks OHI-S dan indeks gingivitis. Hasil: Berdasarkan hasil penelitian terdapat hasil yang signifikan (p<0,05) yang menunjukkan terdapat hubungan antara tingkat kebersihan mulut dengan keparahan gingivitis pada wanita hamil trimester ketiga. Kesimpulan: Pada wanita hamil trimester ketiga terdapat hubungan antara tingkat kebersihan mulut dengan keparahan gingivitis dibandingkan dengan trismester kedua. Meskipun tingkat keparahan gingivitis dipengaruhi oleh tingkat kebersihan mulut peningkatan keparahan gingivitis yang terjadi pada wanita hamil dipengaruhi juga oleh faktor hormon. Hal ini dikarenakan peningkatan hormon pada wanita hamil memuncak pada trimester ketiga kehamilan.

Diabetes mellitus (DM) is a metabolic condition where the body's ability to produce and utilize insulin is impaired; thus, wound healing process is slower than usual in patients with DM. Lemon pepper has both antioxidant and anti-inflammatory properties. This study aimed to investigate the effect of topical application of lemon pepper fruit ethanol extracts on the healing process of oral traumatic ulcers in diabetic rats. This study was performed at the Pharmacology Laboratory, Faculty of Medicine, Universitas Prima Indonesia from September 2021–October 2021. Thirty males diabetic Wistar rats were thermally injured on the lower labial mucosa and divided into five groups: control, standard, and lemon pepper gel 5%, 7.5%, and 10% groups. The ulcer size was measured after injury and on the 7th and 14th day. On the last day, all rats underwent both routine blood count and histology study for oral ulcer tissue. On the 14th day, all treatment groups showed some significant difference wound contraction, with the highest tendency of wound contraction seen in both lemon pepper gel 10% and standard groups (62.50%. p-value =0.001). The improvement of wound contraction was also supported by reduced white blood cell count (p-value<0.05) in routine blood count and regeneration of epidermis and dermis tissues in the histology study. Hence, it can be concluded that the lemon pepper extract gel in all concentrations has good physical stability and the lemon pepper gel with the highest concentration group presents the best ulcer healing activity compared to other concentrations and has similar ulcer healing activity as the standard group that receives Kenalog® in Orabase.

Hospital Health Promotion (HHP) is an effort by hospital management to improve the ability to accelerate patient recovery and improve their health by implementing clean and healthy living behavior (CHLB). This study aims to analyze the application of health promotion management of CHLB in the era of the covid-19 pandemic. This research used a sequential explanatory design located at the RSU Royal Prima Medan with a quantitative sample of 111 patient assistants and qualitative research informants. Data were obtained using questionnaires and in-depth interviews. Based on the research results that 63 respondents have bad CHLB. Data were analyzed using chi-square found that knowledge and attitude have the most significant influence on the implementation of CHLB with p = 0.002 of attitude, followed by p = 0.014 of knowledge and p = 0.019 of HHP. The results of multiple logistic regression indicate that HHP is the most dominant variable that can affect CHLB. In contrast, p = 0.002 of attitude, p = 0.014 of knowledge, and followed by p = 0.019 of HHP. This research also ensured the significance of CHLB as a new approach that may contribute to the advancement of knowledge on hospital management in the pandemic situation.

Intoduction: Health is the condition of the entire body and body parts of an individual who is free from disease both physically, mentally and socially, thus enabling the individual to be able to carry out daily activities more productively. However, many people neglect their own health, especially in the field of dental and oral health. Caries is one of the most common oral and dental problems. The prevalence of dental caries in Indonesia is high, namely 88.8%. Dental caries is caused by Streptococcus mutans bacteria which plays a role in the conversion of sucrose to lactic acid. Infection due to Streptococcus mutans bacteria can be treated by taking antibiotics. Apart from drugs, antibiotics can also be obtained from natural ingredients, one of which is the tintir castor plant (Jatropha multifida Linn) or commonly known as the betadine. Objective: To see the effect of the antibacterial content of tintir leaves against Streptococcus mutans bacteria and to determine the differences in the antibacterial effect of betadine leaf extract (Jatropha multifida L.) from a concentration of 25%, 50%, 75%, and 100% against Streptococcus mutans. Methods: The type of research used in this study was a laboratory experimental study with a post-test-only control group design as the research design and to test the sensitivity of bacteria using the paper disc diffusion test. Data analysis using One-Way ANOVA. Result: The results of this study indicate the effect of tintir castor leaf extract (Jatropha multifida L.) in inhibiting the growth of Streptococcus mutans bacteria.

This study aims to analyze drug formulations in the pharmaceutical installation at the Royal Prima General Hospital Medan. The method in this research is descriptive qualitative. The results showed that the hospital had prepared formularies, maintained formalities, supervised adherence to formulary use, and proposed formulae in pharmaceutical installations. In conclusion, the hospital has carried out a drug formulary in the pharmaceutical installation.   Keywords: Drug Formulary, Pharmacy Installation