No abstract

ÖzAmaç: Obezite günümüzde giderek artan en önemli sağlık sorunlarından biridir. Bu çalışmada, obez hastaların vitamin D düzeyleri, C-reaktif protein (CRP), hemogram parametreleri ve kan grupları ile beden kitle indeksi arasındaki ilişkiyi incelemek amaçlanmıştır.Gereç ve Yöntem: Çalışmaya iç hastalıkları polikliniğine kilo vermek için başvuran ve diyet yapmak isteyen 161 kişi alındı. Hastalar beden kitle indeksine göre iki gruba ayrıldı. Demografik ve laboratuvar verileri hasta kayıtlarından elde edildi.Bulgular: Çalışmaya alınan 161 olgunun yaş ortalaması 31±8, kadın olgu sayısı 150 (%93) ve erkek olgu sayısı 11 (%7) idi. Obez olan bireyler obez olmayanlarla karşılaştırıldığında yaş, bel çevresi, yağ, yağ kitlesi, yağsız vücut kitlesi, total vücut suyu, bazal metabolizma hızı artmış iken yüksek dansiteli lipoprotein düzeyleri anlamlı derecede düşüktü. Obez bireylerde obez olmayanlara göre açlık kan şekeri, HbA1c, insülin direnci ve C-reaktif protein, sistolik ve diyastolik tansiyon değerleri arasında anlamlı fark vardı. Obezite ile cinsiyet arasında ilişki yoktu (Pearson Kikare test 0.455, p=0.500). Obez olan ve olmayan gruplar arasında D vitamin düzeyleri bakımından anlamlı fark yoktu (Mann-Whitney U test 2881, p=0.653). Ancak gruplar D vitamini yeterli ve yetersiz diye kategorize edildiğinde D vitamini ile obezite arasında istatiksel olarak anlamlı ilişki vardı (Pearson Ki-kare test 5.575, p=0.0189). Obezite ile hemoglobin, nötrofil, lenfosit, nötrofil/lenfosit oranı ve trombosit/lenfosit oranı bakımından anlamlı fark yoktu. Obezite ile kan grupları ve Rh bakımından anlamlı ilişki yoktu. Sonuç: D vitamini yetersizliği ile obezite arasında anlamlı ilişki vardı. D vitamini yetersizliği artmış insülin direnci ile birlikte idi. Bu durum D vitamini yetersizliğinin kendisi veya obezite gelişim sürecinde D vitamin metabolizmasındaki farklılıklarla açıklanabilir. Ayrıca CRP'nin artması obez bireylerde enflamasyonu göstermede yararlı bir marker olabilir. Anahtar Kelimeler: Obezite, D vitamini, C-reaktif protein, hemogram, kan grubu Obezite ile D vitamini, C-reaktif protein, hemogram parametreleri ve kan grupları arasındaki ilişki AbstractAim: Obesity is one of the most important and growing health problems of today. We aimed to search for possible association between obesity and vitamin D as well as inflammatory and hemogram parameters. Material and Method:In this study 161 patients presented to internal medicine outpatient clinic with an intention to enter a weight loss program for obesity has been included. Patients were divided into obese and non obese groups. Demographic and laboratory data were recorded. Results:Mean age was 31±8 and 93% of patients were women. Age, waist circumference, fat%, fat mass, free fat mass, total body water and basal metabolic rate were significantly higher while high density lipoprotein was significantly lower in obese patients. Similarly, fasting blood sugar, insulin resistance, C-reactive protein (CRP) and blood pressure were significantly higher in the obese group. Obesity and gender...

Aim We aimed to investigate the relationship between serum pregnancy-associated plasma protein A (PAPP-A) levels and obstructive sleep apnea syndrome (OSAS). Materials and Method 44 patients with OSAS and 44 healthy adults were included in this study. The participants having rheumatic or systemic inflammatory disease, advanced liver or kidney failure, diabetes, heart failure, hypertension, pregnancy, prerenal azotemia, known history of coronary artery disease, any pulmonary disease, rhinitis, or atopy, history of major trauma or surgery within the last six 6 months, and inhaled nasal or systemic corticosteroid use or other anti-inflammatory medications and those with <18 years of age were excluded. Serum PAPP-A levels were determined by the Elisa method with the immune sandwich measuring method. Statistical analysis of the study was performed with SPSS 17.0 statistical analysis package program, and p < 0.05 was considered as significant. Results Serum PAPP-A levels of patients with OSAS (2.350 ng/ml (0.641–4.796)) were significantly higher (p < 0.001) when compared with healthy controls (0.971 ng/ml (0.109–2.679)). There was a statistically significant difference in serum PAPP-A levels between groups of OSAS patients according to the classification of OSAS severity. Between the groups of patients with OSAS, serum levels of PAPP-A in moderate group was significantly higher when compared with severe OSAS group (p < 0.001). There was positive correlations between PAPP-A levels and night minimum (p=0.042, r=0.309), and average oxygen levels (p=0.006, r=0.407). There was a negative correlation between PAPP-A levels and AHI (p=0.002, r=−0.460). Conclusion Higher PAPP-A levels in OSAS patients that were found in this study show inflammatory component in OSAS.

Poland syndrome describes the congenital absence of the pectoralis major and minor muscles on one side of the body accompanied by chest and upper extremity deformities on the same side. However, the only constant finding of the syndrome is the absence of the sternocostal component of the pectoralis major muscle. This finding may be accompanied by additional findings on the same side such as absence of pectoralis minor muscle and of ribs 2 to 5, under-development of breast tissue, latissimus dorsi, serratus anterior and external oblique muscles. The incidence is approximately 1 in 30 000 live births and is more common in men than in women. It mostly holds the right hemithorax of the body. Here we present a 20-year-old male patient without complaints, diseases or other functional anomalies, who has hypoplasia of the right hemithorax, palpation indicating hypoplasia of the pectoral muscle group, and thoracic CT is showing a lack of pectoral muscles.

Chylothorax is a rare clinical condition caused by the accumulation of lymphatic fluid in the pleural space.Chylothorax often results in thoracic trauma and malignant obstruction. More rare causes are tuberculosis, infanjiomiyomatosis, venous thrombosis, congenital lymphatic malformation, nephrotic syndrome, hypothyroidism, cirrhosis, chemotherapeutic drugs, sarcoidosis and idiopathic chylothorax. A 77-year-old female patient with a one year history of colon cancer and post-op chemotherapy was referred to us with the suspicion of metastasis upon detection of lymphadenomas and pleural effusion during a thoracic CT in follow-up. Thoracentesis was performed for the pleural effusion of the patient and chylous fluid was aspirated. The diagnosis of chylothorax was confirmed by pleural fluid biochemical analysis. Results were consistent with tuberculosis from the biopsy performed on synchronous lymph nodes. Due to multiple causes in the etiology of chylothorax, we presented our case.

Objective: Skin prick test is an easy, cheap, safe, fast, and frequently used test to identify allergic diseases. Several factors such as genetic tendency, climate, humidity, vegetation, and altitude effect development of allergies. Our goal was to determine the allergic susceptibility of allergic patients in Sirnak City. Material and Methods: Medical files of 240 patients who referred to our Chest Disease policlinics in Sirnak State Hospital between February 2011 and June 2011 with respiratory complaints suggestive of allergic diseases such as asthma and allergic rhinitis, were retrospectively reviewed. Skin prick test results were evaluated according to age and gender. Results: 240 patients were included in the study, 127 (52.9%) were male and 113 (47.1%) were female. The most common allergic reaction was against grasses, observed in 41 patients (17.1%). The other common allergic reactions were against grains, in 28 patients (11.6%); D. Farinea in 17 patients (7.1%); D Pteronyssinus in 11 patients (4.6%); grass mix in 9 patients (3.7%). Conclusions: Reactions were most commonly observed in the age group of 10-19 years. Asthma and allergic rhinitis patients in Sirnak City should particularly be careful against grasses, grains, and house dust mites.

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Aim: Lung cancer is a type of cancer that is usually diagnosed late and has a low life expectancy due to its incidence, high mortality, and initial asymptomatic course. Sleep disorders and related fatigue are common complaints for cancer patients. This study aims to examine sleep quality according to physical activity levels in individuals with lung cancer.Methods: This study was carried out between December 2021 and March 2022. Individuals diagnosed with lung cancer in Bolu Abant İzzet Baysal University Faculty of Medicine Chest Diseases Outpatient Clinic were retrospectively analyzed. 100 individuals were included in the study. Individuals diagnosed with lung cancer in the chest diseases department of a tertiary care center were retrospectively analyzed. Physical activity level with the International Physical Activity Questionnaire; sleep quality with the Pittsburg Sleep Quality Index; dyspnea with Modified Medical Research Council Scale; performance status with Eastern Cooperative Oncology Group; functional disability with Karnofsky Performance Status; Pain was evaluated with a numerical rating scale.Results: 52.0% of the individuals included in the study were sedentary. There was no difference between the two groups in terms of mean age (p=0.123), body mass index (p=0.157), disease duration (p=0.342), and length of hospital stay (p=0.273). There was a difference between the two groups in terms of Eastern Cooperative Oncology Group (p=0.001), Karnofsky Performance Status (p=0.001), and total score of Pittsburg Sleep Quality Index (p=0.001).Conclusion: In our study, it was found that the total sleep quality score of the physically active group was better than the sedentary group. Physical activity is a modifiable lifestyle behavior with positive physiological and psychological health consequences and a potential non-pharmacological intervention for poor sleep quality.