A case of coincident basophilic chronic myelogenous leukemia and pulmonary tuberculosis is reported. Marked elevations in serum histamine levels were associated with maturity onset‐bronchial asthma which was controlled with antihistamine medication. The diagnosis of tuberculosis was established by pleural fluid cultures. The diagnosis of chronic myelogenous leukemia was established by determination of leukocyte alkaline phosphatase levels and chromosome studies. The importance of such studies in cases of tuberculosis with leukemoid reactions is stressed.
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