SummaryThe prevalence of radiographically ascertained vertebral fractures in a random sample of 413 in Mexican men is 9.7% (95% CI 6.85–12.55). Increase of vertebral fracture rises with age from 2.0% in the youngest group (50–59 years) to 21.4% in the oldest group (80 years and over).IntroductionThis is the first population-based study of vertebral fractures in Mexican men using a standardized methodology reported in other studies.MethodsThe presence of radiographic vertebral fractures increases with age. This same pattern was found in Mexican women with steady age increments, but the higher prevalence of fractures in women starts at age 70, whereas in men, the higher prevalence starts a decade later (80 years and over).ResultsThe standardized prevalence per 1,000 men 50 years and over in the Mexican population for the year 2005 is 65.8 (95% CI 29.9–105.5), and it is 68.6 (95% CI 32.2–108.7) in the US population for the year 2000.
General rightsThis document is made available in accordance with publisher policies. Please cite only the published version using the reference above. Full terms of use are available: http://www.bristol.ac.uk/pure/about/ebr-terms The presence of an osteoporotic vertebral fracture improves fracture risk assessment and may change management, so it is vital for healthcare professionals to assess patients for the presence or absence of these fractures. This may be particularly important in the presence of back pain. However, the correlation between low back symptoms and spinal imaging results is poor and the pathophysiology of most low back pain is not known, leading to a common conclusion that spinal radiographs are not appropriate for the assessment of back pain. For individual patients with back pain, spinal radiographs should be considered if they have certain features in the history and examination. As well as the traditional risk factors for osteoporosis, self-reported descriptives of back pain and novel physical examination findings have been shown to make the presence of vertebral fractures more likely. Systematic approaches have the potential to improve bone health across the population, but need to be targeted to be cost-effective.
KeywordsVertebral fracture Back pain Pain descriptives Physical examinationMini Abstract (50 words)Spinal radiographs should be considered for individual older patients with back pain if they have certain additional features in the history and examination.
This study was aimed to demonstrate that the AmpF'STR 1 Identifiler 1 kit will reliably amplify DNA in a reaction volume of 10 ml. For comparison, the DNA samples were also amplified at the currect in-house PCR reaction volume (12.5 ml). Even though the results showed significant difference in the peak height intensities, the quality of the profiles produced in the reaction volume of 10 ml was similar to those produced in the reaction volume of 12.5 ml. The application of this reduced volume PCR amplification would represent an additional 20% cost saving on the reagents without compromising the quality of the profiles obtained.2015 Elsevier Ireland Ltd. All rights reserved.
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