COVID-19 has a profound impact on the world of work globally. It has altered the social fabric of the workplace and significantly accounts for the loss of normalcy in the world of work. As this threat continues, this paper sought to critically review the impact of COVID-19 on specific areas of the world of work. The study established the link between nCov and global loss of jobs. It critically examined how COVID-19 impacts on teleworking, occupational safety and health, workers mental health, discrimination, physical and social distancing at the workplace. Overwhelmingly, the paper concluded that COVID-19 exacerbates existing cracks in the world of work and its sustainability affects workers’ mental health, social relations, escalate discrimination and unemployment globally. The study suggested policy reforms as global remediation to the negative impacts of COVID-19 on the world of work.