Background: Physical inactivity and resultant lower energy expenditure contribute unequivocally to cardiovascular diseases, such as coronary artery disease and stroke, which are considered major causes of disability and mortality worldwide. Aim: The aim of the study was to investigate the influence of physical activity (PA) and exercise on different aspects of healthgenetics, endothelium function, blood pressure, lipid concentrations, glucose intolerance, thrombosis, and selfsatisfaction. Materials and Methods: In this article, we conducted a narrative review of the influence PA and exercise have on the cardiovascular system, risk factors of cardiovascular diseases, searching the online databases; Web of Science, PubMed and Google Scholar, and, subsequently, discuss possible mechanisms of this action. Results and Discussion: Based on our narrative review of literature, discussed the effects of PA on telomere length, nitric oxide synthesis, thrombosis risk, blood pressure, serum glucose, cholesterol and triglycerides levels, and indicated possible mechanisms by which physical training may lead to improvement in chronic cardiovascular diseases. Conclusion: PA is effective for the improvement of exercise tolerance, lipid concentrations, blood pressure, it may also reduce the serum glucose level and risk of thrombosis, thus should be advocated concomitant to, or in some cases instead of, traditional drug-therapy.

Although age is a dominant risk factor for Alzheimer’s disease (AD), epidemiological studies have shown that physical activity may significantly decrease age-related risks for AD, and indeed mitigate the impact in existing diagnosis. The aim of this study was to perform a narrative review on the preventative, and mitigating, effects of physical activity on AD onset, including genetic factors, mechanism of action and physical activity typology. In this article, we conducted a narrative review of the influence physical activity and exercise have on AD, utilising key terms related to AD, physical activity, mechanism and prevention, searching the online databases; Web of Science, PubMed and Google Scholar, and, subsequently, discuss possible mechanisms of this action. On the basis of this review, it is evident that physical activity and exercise may be incorporated in AD, notwithstanding, a greater number of high-quality randomised controlled trials are needed, moreover, physical activity typology must be acutely considered, primarily due to a dearth of research on the efficacy of physical activity types other than aerobic.

-In many sport disciplines reaction time plays a key role in the sport performance. It is good to point out for example ball games or fighting sports (fencing, karate etc.). The research is focused on detection of the differences in the simple and choice reaction time during visual stimulation among elite, sub-elite fencers and beginners. For the measurement a Fitrosword device and the SWORD software were used. An additional stimulus was added during measuring which should increase the overall number of stimuli, but shouldn't force fencer to any reaction whatsoever. The results from presented study can be compared with Hicks law. The next focus of the study was to identify the difference in reaction time during two different movement tasks with different complexity movement requirements. The research was built up on a hypothesis that the results will differ among different performance groups of fencers. The difference however was overt among beginners and elite fencers (p = 0.0088, d = 0.5) in reaction time during different movement tasks (direct hit vs. lunge). The results of this research could be useful to trainers for training process organisation and increase the effectivity of muscle coordination during several movements in fencing.Key words: Fencing; Visual Stimulus; Reaction time; Additional Stimulus; Hicks law. (esgrima, karate, etc Resumo -Em muitos desportos, o tempo de reação desempenha um papel crucial no resultado desportivo. Como exemplo, pode-se citar jogos que envolvam bola ou desportos de combate

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Aims. The main purpose of this study was to determine the changes in kinematic parameters of ischemic stroke affected upper limbs, during simple functional activity, to determine the most relevant changes. Methods. The OptiTrack system was used for motion capture. To determine upper extremity function in Activities of Daily Living (ADL) tasks. During particular phases, the following matrices were chosen: mean and peak speed, normalized movement unit, normalized jerk and phase movement time. The chosen matrices represent the speed and smoothness profile of end-point data. The the arm-trunk compensation was also taken into consideration. Twenty stroke patients, in early (G1 from 1 to 3 months after stroke) and chronic stage (G2 from 6 months to 1 year), were studied. The large and small cylinder forward and back transporting phases were evaluated. Results. The most significant differences between groups G1 and G2 were in mean and peak speed of the forward transport of the large and small cylinders for the paretic limb. Significant differences were also found for the smoothness (measured by movement unit, mean and peak speed and jerk) where the G2 group had a rougher motion. There were also differences in arm-trunk compensation in the frontal plane. Conclusion. The variables used in the study showed applicability in assessing kinematic parameters in both the early and chronic period after stroke.