Kappaphycus alvarezii is one of the natural resources containing high carbohydrate, and it has potential as an alternative raw material for sugar industry. This study aims to analyze the optimum conditions of the fungi Trichoderma harzianum in degradating polysaccharides from K. alvarezii into sugar. The seaweed was collected in Takalar Sea, South Sulawesi, Indonesia. The fungi was previously activated at 30°C for three days in 2% of seaweed substrate. The efficiency of the T. harzianum in producing biosugar was evaluated under various concentrations of inoculum (5%, 10%, 15% and 20%) and hydrolysis time (0 h, 24 h, 48 h, and 72 h). The result implied that K. alvarezii contain 55,58% of carbohydrate which was dominated by starch 35.83% and cellulose 12.21%. Furthermore, the highest content of sugar indicated by 12,27 g/L of reducing sugar was obtained at the combination of 20% of the fungi and 24h incubation. In conclusion, the fungi T. harzianum has ability to convert carbohydrate of K.alvarezii to sugar through hydrolysis process.
Usaha budidaya Udang Windu (Penaeus monodon) di daerah Maros mengalami berbagai permasalahan, diantaranya sistem budidaya masih tradisional, pelaku utama kebanyakan tidak melakukan seleksi benur dengan baik, dan pelaku utama belum menguasai cara-cara budidaya yang baik. Keberhasilan pembangunan pada bidang perikanan terkendala permasalahan tersebut, juga diduga dipengaruhi oleh kinerja penyuluh perikanan yang belum optimal. Tujuan penelitian adalah untuk mendeskripsikan kinerja penyuluh perikanan; dan menganalisis pengaruh informasi pasar, teknologi dan permodalan masing-masing terhadap pengembangan usaha budidaya udang windu (P. monodon) di Kabupaten Maros. Hasil penelitian kinerja penyuluh perikanan menunjukkan bahwa rata rata pendapat penyuluh perikanan dan pelaku utama terhadap kinerja penyuluh perikanan tinggi, informasi pasar 3,5 (sedang), teknologi 4,3 (tinggi) dan permodalan 3,5 (sedang). Menurut pendapat penyuluh dan pelaku utama keberhasilan pelaku utama rata rata 3,5 (sedang). Pengaruh informasi pasar, teknologi dan permodalan masing masing berpengaruh terhadap pengembangan usaha budidaya Udang Windu (P. monodon) dilihat nilai t hitung lebih besar dari t tabel, t hitung informasi pasar 7,638, teknologi 3,506 dan permodalan 5,597 sedangkan t tabel 1,659.
Kappaphycus alvarezii is one of the natural resources that contains high carbohydrates and has the potential as an alternative raw material for the sugar industry. The aims of this research is to analyze the optimal conditions of the combination of Trichoderma harzianum and Saccharomycopsis fibuligera in degrading polysaccharides from K. alvarezii into sugar. T. harzianum and S. fibuligera were activated three times at 30° C in 2% seaweed substrate. The method used was a combination of hydrolysis and fermentation to produce evaluated bio sugar in various concentrations of inoculum (5%, 10%, 15%, and 20%) and time (0 hour, 24 hours, 48 hours, and 72 hours). Based on the results, hydrolysis with an inoculum concentration of 20% for 24 hours showed the highest total sugar production. Followed by fermentation with S. fibuligera which produced glucose and galactose which is 1.74 g/L and 9.93 g/L. In conclusion, this research demonstrates the ability of T.harzianum and S. fibuligera to convert carbohydrates from K. alvarezii to produce biosugar through a combination of hydrolysis and fermentation methods.
Malaria is one of the most important public health problems worldwide, with nearly half of the global population exposed to the risk of contamination. The disease is found in 91 countries, mostly in the tropics and subtropics of the planet. There are several previous research that identifies Plasmepsins as a potential target to develop novel antimalarial drugs from the malaria parasite Plasmodium that play a role in the breakdown of globin into amino acids. Given the above, it is important to find novel and effective drugs that can decrease this disease, especially from natural products such as medicine. Seaweed is a potential source of bioactive compounds to be used as antimalarials, such as species from the genera Laurencia and Halymenia. This recent study has studied the molecular docking approach to identify the potential of Halymenia sp. and Laurencia sp. against Plasmepsin by using PyRx 0.8 software. It showed that the compounds in Halymenia sp. and Laurencia sp. were able to react and inhibit the action of plasmepsin, seen from the binding affinity value, which was quite small at -4.3, this value is higher than the two bioactive compounds in seaweed, namely Stigmasterol and p-hydroxybenzaldehyde which have binding affinity values of -8.5 and 6.5, respectively. Judging from this, the compounds contained in Laurencia sp and Halymenia sp have potential as candidates for antimalarial drugs.
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