Dengue has emerged as an alarming concern exhausting the already tired healthcare professionals during the ongoing pandemic of COVID-19. There has been an epidemic of dengue fever with massive underreporting; this might be a result of limited resources as well as the inability to reach healthcare facilities as a consequence of reluctance seen in patients due to the scare of COVID-19. Acute pain in the abdomen has been an alarming sign of dengue; however, its association with acute pancreatitis is rare. We report a case of a 21-year-old young male with fever, vomiting, and pain in the abdomen who was diagnosed with acute pancreatitis as a complication of dengue infection. We highlight the importance of screening for acute pancreatitis in patients with dengue presenting with pain in the abdomen as it may be a rare but important complication of dengue fever.
Hyperthyroidism in pregnancy is a condition that results from an excess of beta-human chorionic gonadotropin hormone resulting in gestational thyrotoxicosis. This thyrotoxicosis of pregnancy might be linked with hyperemesis gravidarum and is usually a self-limiting disease. Hyperthyroidism can cause hypokalemic periodic paralysis, which presents as pure motor areflexic flaccid paralysis. In severe cases, it may involve respiratory muscles and cause hypercapnic respiratory failure requiring invasive ventilation. A positive feed-forward cycle of hypokalemia could be triggered by the loss of function of inward rectifier potassium channel 18 (Kir2.6) along with the increased activity of sodium, potassium-adenosine triphosphatase (Na⁺/K⁺-ATPase). Hyperthyroid periodic paralysis is characterized by biochemical hyperthyroidism, normal urine potassium excretion, and electrocardiography abnormalities.
We report a case of a 23-year-old female (G2P0L0A1) who had severe hyperemesis gravidarum and later on developed flaccid quadriplegia. Her thyroid profile revealed hyperthyroidism. She later developed hypercapnic respiratory failure and was managed by potassium replacement and invasive ventilation.
This observational pilot project was performed as background to eventually create a rapid, automated and accurate assessment of RV systolic function in variable clinical subgroups. We propose new parameters that characterize the global systolic function of the right ventricle with a simple linear measurement.
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