Summary A coating made of a styrene‐acrylate copolymer and containing triclosan (87 ± 9 mg triclosan cm−3 coating) was evaluated as an antimicrobial layer for packaging materials. In both agar diffusion tests and liquid culture tests, inhibition of growth of Enterococcus faecalis by the triclosan‐coating was observed. Triclosan in the coating was not released into the water. Using a solution of 10% aqueous ethanol to simulate aqueous/acidic foods, a very small portion of the triclosan was quickly released with an estimated apparent partition coefficient of 1.7 × 10−5. When using n‐heptane, to simulate fatty foods, most of the triclosan was extracted with an estimated apparent partition coefficient of 5.5 × 10−2.
The encapsulation of thymol and geraniol in beta-cyclodextrin (beta-CD) and modified starch (MS) by spray- and freeze-drying was studied. The formation of thymol/beta-CD and geraniol/beta-CD inclusion complexes was confirmed by differential scanning calorimetry (DSC). Oxidative DSC revealed that the monoterpenes enclosed in the beta-CD cavity were protected against oxidation, remaining intact in temperatures at which free monoterpenes were oxidized. Phase solubility studies showed that the inclusion complexes of thymol and geraniol with beta-CD are more soluble in water than the free molecules themselves. Furthermore, in order to evaluate the fraction of monoterpenes that can be released from their complexes with MS in aqueous media, a series of release experiments were conducted.
The release phenomena ofpropyl paraben fiom a polymer coating to water and three food simulating solvents (1 0% aqueous ethanol, 50% aqueous ethanol, nheptane) were studied for antimicrobial packaging applications. The effects of food simulating solvent, initial concentration in the coating and temperature on the propyl paraben release were examined. The initial concentration of propyl paraben in the coating rangedfiom 1.26 x lV to 10.52 x 10 g/m' and the temperaturefiom 5.5 to 30C. For water, the release was controlled by Fickian dirusion with constant difision coefficient (7-11 x I@" cmz/s at 30C), and independent of the initial concentration. For 10% ethanol, the release followed again the Fickian model with constant dimion coefficient (30-40 x I @ ] I cmz/s at 30C). For 50% ethanol and n-heptane, the release was instantaneous and not controlled by Fickian dimion. For the release into water, the activation energy for d i f i i o n from the Arrhenius relationship was around 88 kl/mole.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.