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N,O-heterocycles containing the dicarbonyl ring play a significant role in heterocyclic and therapeutic chemistry. Since the discovery of 1,3-diketones, numerous research works have been achieved regarding the synthesis and its chemical reactivity. In this review, we have described the most relevant publications involving β-diketone compounds published during the period between 2018 to date. In addition, we include the 1,3-diketones-based heterocyclic compounds prepared by various synthetic methodologies.
organométallique et valorisation des substances naturelles, Faculté des sciences, université ibn zohr, BP 8106, Dakhla Agadir 80000.
conclusion
References
Efficient Synthesis of pyrazolo-enaminone derivatives and evaluation of their biologicalThe chemistry of heterocycles has experienced a boom in recent decades. which has resulted in an impressive number of compounds containing in their structure at least one heterocycle. In fact, of the 65 million chemical compounds, more than two thirds contain a heterocyclic system ( 2009statistics). Heterocycles are important, not only because of their abundance and extraordinary diversity, but above all because of their usefulness in the biological, medicinal and (vitamins, hormones, antibiotics, etc.), that in the industrial sector, and technological (corrosion inhibitors, dyes, stabilizers, pesticides, herbicides, etc).. Among the different classes of heterocyclic compounds, mainly nitrogenous structures are present in many natural compounds of plant, animal or synthetic origin. Among these are the pyrazolo-enaminones.
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