AimTo characterise current insulin pump settings used in young patients with type 1 diabetes mellitus (T1DM) and their relationship to glycaemic and weight control. MethodsThis retrospective study included patients aged <18 years old with T1DM duration >1 year who were using the Medtronic pump device. Data from the insulin pumps including number of blood glucose (BG) tests per day, basal and bolus insulin parameters, carbohydrate ratio (CR) and insulin sensitivity factors (ISF) were averaged over 14 days for statistical analyses. Anthropometric data and recent HbA1c was also recorded.

The characteristic form of adolescent onset ED exists among adolescents living in India. A multidisciplinary approach to treatment is essential for a good outcome. This article was written to sensitize health care professionals, pediatricians in particular about the existence of ED among adolescents living in India and the current acceptable principles of management of this potentially fatal illness.

Isolated pulmonary involvement in Langerhans Cell Histiocytosis (LCH) is rare in childhood. The authors report a 6-y- old boy presenting with recurrent pneumothorax, whose CT thorax showed diffuse pulmonary cystic lucencies bilaterally. Biopsy of the lesions confirmed pulmonary LCH with Cd1a and S 100 positivity.

Background: We present a 6 year old boy with type I Gaucher treated from 16 months with ERT, developing focal Gaucheroma in the liver at 3.5 years.

ObjectiveThe objective of this study was to describe the renal manifestations in children 0–18 years of age diagnosed with tuberous sclerosis complex (TSC) at a tertiary hospital in South India.MethodsData of children with TSC, who presented to Christian Medical College Vellore Hospital from January 2008 to January 2013, were analysed by a retrospective chart review. The cases were identified from outpatient records and underwent ultrasonography, urine analysis and examination of serum creatinine to recognize renal involvement.ResultsTwenty-five children with TSC were identified. Two children did not have imaging studies available and were excluded from the analysis. The age of the included children ranged from 5 days to 15 years with a median age of 8 years. Seventy-four per cent (17/23) were males. Ten of the 23 children had evidence of renal involvement (43.5%). Of the 10 children with renal involvement, 6 had angiomyolipoma (60%), 5 had renal cysts (50%) and 1 had suspected renal cell carcinoma. In two children both angiomyolipoma (AML) and cysts were noted. One child was found to have proteinuria. The rest of the children had no evidence of proteinuria and had normal creatinine clearance.ConclusionWe conclude that all children with TSC should be screened for renal involvement and regular follow-up should be arranged.