Three newly synthesized copper complexes with pyridoxal semicarbazone (PLSC), as ligand, after being subjected to biological tests, showed anticancer activity. As ligand PLSC is biologically active, the results of biological activity are as expected. Specifically, an activity was demonstrated in breast cancer cells (MCF7 and MDA MB 231) and proliferative cells (MCF7).
The aim of this research was developed in order to determine and analyze the level of environmental awareness of students from primary and secondary schools. Environmental awareness is an essential product of environmental education. Conducted research included analytical and descriptive method. The research instrument was the survey designed for purpose of the research. There were 198 students of primary and secondary school involved in the survey which included 28 questions. Following statistic parameters were used for results analysis: mean value, standard deviation (SD) and coefficient of variation (CV). The existence of difference between opinions of students (statistic significance of differences between mean values) was determined by variance analysis (ANOVA) or using independent t-test.
Providing environmental knowledge was one of the objective components in implementing Environmental Education other than enhancing awareness, attitude, skills and behaviour towards environmental among students. According to Tanaka (2000), environmental knowledge can be defined as individual understanding on how environment functioning; how human interact with the environment; how environmental problems arise; and in what
The syntheses of complexes of Cu(II) with biological active ligand, pyridoxal thiosemicarbazone (PLTSC) and its derivative, pyridoxal S-methylisothiosemicarbazone, are described. All coordination compounds were characterized by elemental analysis, molar conductivity and infrared spectra. The crystal and molec-is determined by single-crystal X-ray crystallography, too. The thermal decomposition of all the ligands and complexes was determined by simultaneous TG/DSC measurements. The decomposition mechanisms were compared and analyzed from the aspects of the relationships between the structures of the compounds and their thermal decomposition pattern.
The title compound, C9H13N4O3(+)·NO3(-), is the first structurally characterized Schiff base derived from semicarbazide and pyridoxal. Unusually for an unsubstituted semicarbazone, the compound adopts a syn conformation, in which the carbonyl O atom is in a cis disposition relative to the azomethine N atom. This arrangement is supported by a pair of hydrogen bonds between the organic cation and the nitrate anion. The cation is essentially planar, with only a hydroxymethyl O atom deviating significantly from the mean plane of the remaining atoms (r.m.s. deviation of the remaining non-H atoms = 0.01 Å). The molecules are linked into flat layers by N-H···O and C-H···O hydrogen bonds. O-H···O hydrogen bonds involving the hydroxymethyl group as a donor interconnect the layers into a three-dimensional structure.
H 2 CO 3 ) in presence of Na 2 CO 3 ·10H 2 O, pyridoxal-aminoguanidine (PLAG; H 2 L) was obtained. Ligand and appropriate salt CuCl 2 are coordinate, and form the following complex: green-brown, hexa-coordinated, octahedral structure, dimmer-complex Cu(II) formula [Cu(PLAG)(NCS) 2 ] 2 . This paper presents a synthesis and crystal structure of complex with Schiff-based ligand.
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