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Background: Endometrial carcinoma is the most common cancer of the female genitalia and its prevalence is 2% to 3% along the females' lifetime. This adenocarcinoma is diagnosed in the early stages because the patients become symptomatic early in the course of disease. The correlation of the lower uterine segment involvement (LUSI) with the recurrence, and the survival rates in patients with endometrial adenocarcinoma are always questionable. Confirming the prognostic significance of LUSI can fundamentally improve the current state of patients' surveillance. The current study aimed at investigating the association of lower uterine segment involvement with deep myometrial invasion in endometrial adenocarcinoma. Methods: In the current retrospective cohort study, 54 patients with stage I endometrial endometrioid adenocarcinoma who underwent surgery in Mirza-Koochak-Khan Hospital, Tehran, Iran, from 2004 to 2014 were divided into 2 groups according to the presence of LUSI. In the current cohort study, the data from the patients exposed to LUSI were obtained by questionnaires to measure deep myometrial invasion besides post-operative adjuvant radiotherapy. The median of follow-up period was 48 months for all of the patients, which started after their surgery, and the measurement period for variables were similar to those of the follow-up period, which was 48 months. They were compared regarding to age, tumor grade, depth of myometrial invasion, lymphovascular involvement, extra uterine diseases, the extent of lymphadenectomy, adjuvant therapy, recurrence rate, time, and location. The data analysis was conducted by the SPSS v.16 statistical software (Chicago, IL, USA) at the significance level of 5%. In the investigation, Chi-square, the Kolmogorov-Smirnov, t test, and the Mann-Whitney U tests were used. Results: Group 1 consisted of 13 patients with LUSI and group 2 had 41 patients without LUSI divided by a non-random sampling method. According to the results of the Mann-Whitney U test, there was a significant difference between the mean age of patients with LUSI and that of the ones without LUSI (P = 0.03). It showed that the mean age in the former group was significantly higher than that of the latter. A Chi-square test showed no significant association between the lymphovascular involvement and the presence of LUSI (P = 0.1). The Fisher exact test showed that patients with LUSI had significantly higher rate of radiotherapy after surgery rather than the ones without LUSI (P < 0.001). Conclusions: In conclusion, there was a significant association between the lower uterine segment involvements with deep myometrial invasion in the endometrial endometrioid adenocarcinoma. In other words, there was a significant difference in the depth of myometrial invasion between the groups, and the patients with LUSI had deeper myometrial invasion (the Mann-Whitney U test, P < 0.001).

Serum progesterone level showed a negative correlation with the pain score after cesarean section.

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Introduction: The usage of information and communications technology (ICT) in educational systems is a flowing and active educational programme. However, prior to its usage, an attempt should be made to identify the factors influencing such a phenomenon. This study aims to identify the psychological and job-related factors affecting the intention to use ICT among teachers in Shiraz. Methods:The present study is applicable from the research type perspective, descriptive from the procedure perspective, and correlative from the research design perspective. The sample includes all teachers in Shiraz. To determine the sample size (n = 255), stratified-cluster random sampling and Cochran's formula were used. Several questionnaires were completed by the participants, such as subjective norm, task-technology fit, perceived ease of use, perceived usefulness, and intention to use. Validity (in terms of content) and reliability of the questionnaires were confirmed by comments from experts and professors and Cronbach's alpha coefficient (0.69) respectively. Data analysis was done using structural equation modelling with LISREL software (version 8.8).Results: Task-technology fit, perceived ease of use, intention to use, and subjective norm variables directly or indirectly affect the intention to use ICT. Among these, subjective norm variable has the highest direct impact (0.33) upon the intention to use ICT, while, task-technology fit variable has the highest indirect impact (0.08). Moreover, the highest and lowest total effects on the aforementioned variable are associated with the impact of task-technology fit (0.39) and perceived ease of use (0.27) respectively. Conclusions:The findings indicate that the predicted model could provide useful information for the educational authorities with respect to the importance of job-related and psychological factors that directly or indirectly affect the intention to use ICT among teachers.