A doença COVID-19 surgiu em dezembro de 2019 e desde então disseminou-se por todo o mundo, obrigando à adaptação de estruturas e reorganização de serviços hospitalares, e colocando à classe médica o grande desafio de em tempo recorde, se atualizar e se manter em constante aprendizagem. Para os sobreviventes desta doença, a eliminação do vírus SARS-CoV-2, é apenas o começo de um caminho de recuperação incerto e desconhecido. De facto, segundo o conhecimento atual, o que se segue à fase aguda da infeção por SARS-CoV-2 depende da extensão e gravidade da invasão viral nos diferentes tipos de células e órgãos, mas apesar do número crescente de artigos publicados no último ano, ainda não existe uma descrição inequívoca, de um quadro clínico típico das consequências da COVID-19. Com o objetivo de conhecer o estado da arte sobre este tema, as autoras fazem uma revisão do que tem sido publicado sobre complicações/sequelas da infeção por SARS-CoV-2.
Approximately 10% of patients experience symptoms of Post COVID-19 Condition (PCC) after a SARS-CoV-2 infection. Akin acute COVID-19, PCC may impact a multitude of organs and systems, such as the cardiovascular, respiratory, musculoskeletal, and neurological systems. The frequency and associated risk factors of PCC are still unclear among both community and hospital settings in individuals with a history of COVID-19. The LOCUS study was designed to clarify the PCC’s burden and associated risk factors. LOCUS is a multi-component study that encompasses three complementary building blocks. The “Cardiovascular and respiratory events following COVID-19” component is set to estimate the incidence of cardiovascular and respiratory events after COVID-19 in eight Portuguese hospitals via electronic health records consultation. The “Physical and mental symptoms following COVID-19” component aims to address the community prevalence of self-reported PCC symptoms through a questionnaire-based approach. Finally, the "Treating and living with Post COVID-19 Condition" component will employ semi-structured interviews and focus groups to characterise reported experiences of using or working in healthcare and community services for the treatment of PCC symptoms. This multi-component study represents an innovative approach to exploring the health consequences of PCC. Its results are expected to provide a key contribution to the optimisation of healthcare services design.
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