Reports about presence and toxicity of Cd2+ in different chemical industrial effluents prompted the researchers to explore some economical, rapid, sensitive, and accurate methods for its determination and removal from aqueous systems. In continuation of series of investigations, adsorption of Cd2+ onto the stem of Saccharum arundinaceum is proposed in the present work. Optimization of parameters affecting sorption potential of Cd2+ including pH, contact time, temperature, sorbent dose, and concentration of sorbate was carried out to determine best suited conditions for maximum removal of sorbate. To understand the nature of sorption process, linear and nonlinear forms of five sorption isotherms including Freundlich and Langmuir models were employed. Feasibility and viability of sorption process were evaluated by calculating kinetics and thermodynamics of the process, while error analysis suggested best fitted sorption model on sorption data. Thermodynamic studies demonstrated exothermic nature of reaction, while kinetic studies suggested pseudo-second order of reaction.
The present study investigates the antidiabetic potential of polyphenol extracts purified from guava pulp, seeds and leaves using an in vivo experiment on albino rats. The polyphenols from guava pulp, seeds and leaves were extracted using methanol solvent and the sonication method while being evaluated by total phenolic contents and radical scavenging activity assay. The proximate composition of powders revealed that ash, protein and total sugars were significantly (p < 0.05) higher in leaves and seeds, while vitamin C was highest in pulp. Total phenolic and antioxidant activities were highest in pulp followed by leaves and seeds. The findings of feed intake and body gain revealed that the supplementation of polyphenols, especially from pulp, significantly (p < 0.05) increased the feed intake, which resulted in increased body weight. Moreover, total cholesterol (TC) and low-density lipoprotein (LDL) levels were significantly (p < 0.05) decreased, while the level of high-density lipoprotein (HDL) was increased in groups fed with polyphenols from guava pulp compared to both (+ive and –ive) control groups. Furthermore, blood glucose and triglycerides were significantly (p < 0.05) decreased in supplemented groups compared to the control group of diabetes mice, which resulted in the inhibition of α-amylase and glucose transport. Besides this, packed cell volume (PCV), mean corpuscular volume (MCV), hemoglobin, red blood cells (RBCs), white blood cells (WBCs) and platelet levels were increased significantly (p < 0.05) in pulp’s extract followed by leaves and seeds compared to both control groups. Overall, the antidiabetic potential of different extracts was in the following order: pulp > leaves > seeds. The findings suggest the feasibility of adding 200–250 mg/kg.bw of polyphenol extracts of pulp as an alternative to diabetic drugs.
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