Aim The aim of the present study was to investigate the awareness of oral cancer among adults in Jakarta, Indonesia, and explore the factors influencing it. Methods A previously‐tested questionnaire on 1000 adults in Jakarta was used in the present study. The data included sociodemographic factors and answers to assess the awareness of oral cancer, early signs and symptoms, risks factors, lifestyles, and history of dental visits. Results Only 53.2% of participants were aware of oral cancer. The level of awareness significantly differed by level of education, occupation, and experience of dental visits. Only 30% of patients had been asked about their tobacco and alcohol habits, and had been informed about the hazards of these by their dentists. All of the smokers knew that tobacco increased the risk for oral cancer. However, only a few participants considered alcohol, betel quid chewing, UV light exposure, poor diet, and genetics to play role in the development of oral cancer. Health warnings were the main source of information about oral cancer; the role of health professionals is still quite low and needs to be emphasized. Conclusion Oral cancer awareness is still low among adults in Jakarta; this finding was consistent with other studies conducted in Asia. Educational material suited to particular communities is warranted.

Background: Currently it is believed that human papillomaviruses (HPV) are associated with the development of some oral/oropharyngeal cancers. It has been suggested that these viruses influence carcinogenesis in both smokers and non-smokers. Data on the prevalence of HPV in healthy adults are thus needed to estimate the risk of oral/oropharyngeal cancer. The aim of this study was to assess the prevalence of oral HPV in healthy female adults in Indonesia and Thailand. Materials and Methods: Healthy female students from the Faculties of Dentistry of Universitas Indonesia and Chiang Mai University were asked to participate in this pilot study. DNA was extracted from saliva specimens and screened for HPV16 and HPV18 using PCR. Results: The age, marital status and sexual experience of the subjects between the two countries were not significantly different. Eight (4%) and 4 (2%) samples were positive for HPV16 and HPV18, respectively. Fisher's Exact test found a significant difference between HPV16 positivity in subjects who were married and had sexual intercourse but not for HPV18. Conclusions: This study successfully detected presence of HPV16 and HPV18 DNA in a number of saliva samples from female dental school students. Marital status, experience of sexual intercourse and safe sexual practice are related to the possibility of finding HPV DNA finding in saliva. Dentists, physicians and other health care professionals may gain significant value from the findings of this study, which provide an understanding of the nature of HPV infection and its risk to patient health and disease.

Manifestasi klinis rongga mulut dapat sebagai penanda awal kelainan darah, seperti anemia. Anemia defisiensi zat besi / Iron Deficiency Anemia (IDA) adalah kelainan darah yang paling umum dengan manifestasi rongga mulut khas yaitu glossitis, mukosa mulut pucat, dan angular cheilitis. Seorang pasien wanita berusia 46 tahun mengeluh sakit dalam mulut yang berulang terutama di lidahnya selama hampir 5 tahun. Pemeriksaan klinis ditemukan mukosa mulut pucat, fissure pada sudut mulut, dan atrofi papila lidah. Pemeriksaan laboratorium menunjukkan IDA. Penanganan kasus ini dengan meredakan gejala dalam mulut dan merujuk ke bagian penyakit dalam untuk terapi lebih lanjut. Dokter gigi dapat terlibat dalam menegakkan diagnosis IDA dengan mengetahui tanda dan gejala klinis rongga mulut yang khas.

Infection by Herpes Simplex Virus (HSV) type I and II cause a worldwide medical problems. HSV-I infections are common in oral and perioral area. After primary infection, HSV becomes latent in the dorsal root ganglia and recurrences are caused by many stimuli. Antiviral agents, prevention of transmission, suppression of recurrences are current management of HSV infection. Objective: to discuss the management of Recurrent Intraoral Herpes (RIH) infection. case report: a 21 years old female patient came to hospital with irregular painful ulcers in her mouth preceded by prodrome, followed with eruption and outbreak of vesicles. The first laboratory examination confirmed high titer of reactive Immunoglobulin M (IgM) and IgG of anti HSV-I and HSV-II. She was diagnosed to have RIH and treated with oral Acyclovir, multivitamins, immune stimulant and 0.2% chlorhexidine gargle with good healing. Oral Valacyclovir was given after she had another recurrence, with the result of low episodes of RIH and continuous titer improvement of reactive IgM and IgG of anti HSV-I and HSV-II. conclusion: Oral administration of Valacyclovir as a the oral prodrugs of Acyclovir is effective prophylactic and therapeutic option with many advantages against HSV infection.

Kedokte*" Cigi u"i*rrirJ"a""""" AD3trltct Compr€hensiv€ Managem€nt ofMucous Mrmrane pemphigoid in an Medica y Conpromised patient tDirbet€s Mellirus and Hypertcnsion) (a Case Reporl) , Mucous .membrane pemphigoid (MMp) is.an autoimmune mucocuran€ous bristenng disease characterized by autoanribodies ro comDonents within the basemenr ,;;b;;;;;;*. il" ,"""", ln"y produce risk of scarring ofthe canrhus (stmbt€pharon), inversion ofthe €y€tastes tennop;oniano nauma to ttte comea (trichiasis). We reported a case ofMMp in a 56-year otd femate wiitr "on"offla jio"r". rn"rrn". and hyp€rtension whose ocutar involvemenr has lead ro btind'ness ofrhe righr .y.. ii. ai"el.i "fVVp ** based on the history and clinical findinss jn or ,h.

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Abstract-Lupus erythematosus (LE) is a chronicinflammatory disease caused by interference of the immune system. There are several criteria to establish a diagnosis of this disease including oral mucosal lesions. Oral mucosa lesions are an important part because they can be the initial presentation of LE. The objective of this case report was to describe oral mucosal lesions as initial presentation of LE disease without involvement of other organs. A 47-year-old female came to the Oral Medicine Clinic at RSUPN Cipto Mangunkusumo Jakarta with complaints of a five-month history of soreness on her inner cheek, tongue and severe crusted lips without fever. Patient had been taken drug containing paracetamol and caffeine every day since 2 years ago without any doctor's prescription. Clinical finding seen were erosion and blackish brown crusted on the lips; macular and irregular ulcer, surrounded by reddish color with diffuse borders on the buccal mucosa; sloughing and keratotic papules on the tongue. The working diagnosis on the first visit is Oral Lichen Planus. At the next visit, after clinical evaluation and referral to the Immunological Allergy Department were done, the patient was diagnosed of LE. Topical dexamethasone was prescribed and the patient are required for follow up each one week. The patient given advice to follow Immunological Allergy Department's treatment plan. Oral mucosal lesions may be the initial appearance of LE patient. Early diagnosis is important for LE comprehensive treatment, so that the morbidity can be reduced and survival rate can be increased.

Recurrent oral ulceration usually induced pain and influence patient’s quality of life. Reccurent Aphthous Stomatitis (RAS) is a common disorder with recurring ulcers, affecting the oral mucosa, painful and no other signs of systemic disease. Human Immunodeficiency Virus (HIV) is considered as a predisposing factor for RAS. Lesion of RAS associated with HIV, usually more severe, longer lasting to healing and non specific clinical features. This case report describe clinical features of recurrent oral ulceration in HIV patient.  A 23 year old female came with complaint oral ulceration in soft palate and tongue since 2 months ago. Patient was diagnosis HIV since seven years ago. Several examinations were done to explore possibility of opportunist infection in HIV patient. Intra oral examination showed regular ulcer, with yellowish base, surrounding erythematous halo. The locations of ulcer were in labial mucosa, dorsum and ventral of the tongue, and soft palate. Ulceration in keratinized mucosa and non keratinized mucosa, gives un-specific features mimicking Tuberculous oral ulcer but in this case there was no indurations on all ulcer. Based on anamnesis and clinical examination, the diagnosis of this case is RAS with differential diagnosis of Tuberculous oral ulcer. The therapy given was gold standard of RAS, the outcome was successful without TB therapy. RAS on HIV Patient can give unspecific clinical features, mimicking oral manifestation of opportunist infection commonly occurred in HIV patient.