Revisão J Bras Neurocirurg 23 (3): 217-221, 2012 Maranha LA, Augusto LP, Zanine SC, Araújo JC -Acrania e outras falhas na formação dos ossos do crânio: uma revisão da literatura Acrania e outras falhas na formação dos ossos do crânio: uma revisão da literatura Acrania and other failures in the formation of the skull bones: a literature reviewA acrania é uma malformação congênita rara que cursa com ausência parcial ou total do crânio de fetos humanos. Está associada frequentemente com anencefalia e é, via de regra, fatal em curtíssimo prazo. Existem alguns marcadores pré-natais, sendo a ultrassonografia o exame diagnóstico padrão-ouro. Os autores revisam aspectos relacionados a epidemiologia, fisiopatologia, diagnóstico ultrassonográfico, diagnóstico diferencial entre malformações cefálicas e manejo obstétrico da doença. Palavras Chave: Acrania; malformação de sistema nervoso central; anencefalia.ABSTRACT Acrania is a rare congenital malformation with partial or total absence of skull of human fetuses. It is often associated with anencephaly and is usually fatal in very short time. There are some prenatal markers and the ultrasound is the gold-standard diagnostic method. The authors review aspects of the epidemiology, pathophysiology, ultrasound diagnosis, differential diagnosis of cephalic malformations and obstetric management of the disease.
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