CYP46 influences brain beta-amyloid load, cerebrospinal fluid levels of beta-amyloid peptides and phosphorylated tau, and the genetic risk of late-onset sporadic AD.

No abstract

Pathways and Predictions articles are summaries of multi-process biological responses to chemicals described by extensive datasets. Adverse outcome pathways (AOPs) are one example of this where comprehensive compilations of concepts and evidence comprising a given AOP can be obtained from an open-source AOP Wiki (aopwiki.org).

No abstract