Objective:To describe the epidemiologic characteristics and adverse events of patients submitted to total hip and total knee replacement.Methods:A cross-sectional study retrospectively assessing medical chart data of all total hip and total knee replacements performed at a private hospital, between January 2007 and December 2010 Patients submitted to total hip and total knee replacement, with consent of surgeons were included. Incomplete records and/or missing data of the hospital database were excluded. The categorical variables analyzed were age, gender, type of arthroplasty (primary or secondary), type of procedure, duration of surgery, use of drains, risk of infection, compliance to protocol for prevention of deep venous thrombosis and embolism pulmonary, and compliance to the protocol for prevention of infection. The outcomes assessed were adverse events after surgery.Results:A total of 510 patients were included; in that, 166 admissions for knee replacements (92 male) and 344 admissions for hip replacements (176 female). The mean age of patients was 71 years (range 31-99 years). Adverse events were reported in 76 patients (14.9%); there was no correlation between assessed variables and number of complications.Conclusion:The results showed no individual factors favoring complications in patients submitted to total hip and total knee replacement; hence, surgeons should consider prophylaxis to avoid complications.

In patients with early gastric neoplasia, ESD is safer and is associated with a positive impact on health-related QoL when compared with gastrectomy, without increasing fear of recurrence and new lesions.

Objective:To evaluate effectiveness of the use of platelet-rich plasma as coadjuvant for union of long bones.Methods:The search strategy included the Cochrane Library (via Central) and MEDLINE (via PubMed). There were no limits as to language or publication media. The latest search strategy was conducted in December 2011. It included randomized clinical trials that evaluated the use of platelet-rich plasma as coadjuvant medication to accelerate union of long bones (acute fractures, pseudoarthrosis and bone defects). The outcomes of interest for this review include bone regeneration, adverse events, costs, pain, and quality of life. The authors selected eligible studies, evaluated the methodological quality, and extracted the data. It was not possible to perform quantitative analysis of the grouped studies (meta-analyses).Results:Two randomized prospective clinical trials were included, with a total of 148 participants. One of them compared recombinant human morphogenic bone protein-7 versus platelet-rich plasma for the treatment of pseudoarthrosis; the other evaluated the effects of three coadjuvant treatments for union of valgising tibial osteotomies (platelet-rich plasma, platelet-rich plasma plus bone marrow stromal cells, and no coadjuvant treatment). Both had low statistical power and moderate to high risk of bias.Conclusion:There was no conclusive evidence that sustained the use of platelet-rich plasma as a coadjuvant to aid bone regeneration of fractures, pseudoarthrosis, or bone defects.

Introdução. Os pacientes com acidente vascular cerebral (AVC) podem desenvolver na fase inicial da doença um aumento dos níveis séricos de glicemia, com consequente piora das lesões cerebrais. Um dos principais motivos apontados para a hiperglicemia no AVC é um aumento da resistência periférica à insulina. O objetivodo trabalho é analisar a evolução dos níveis glicêmicos de pacientes não diabéticos internados por acidente vascular cerebral na fase aguda. Método. O trabalho é retrospectivo, por levantamento dos prontuários dos pacientes internados no período de agosto de 2005 até janeiro de 2007. Resultados. A evolução foi diferente para os grupos de faixas etárias acima e abaixo de 60 anos (p=0,02), e para aqueles pacientes que ecessitaram receber intervenção para correção dos níveis de glicemia (p=0,03). Conclusão. O estudo confirmou uma maior dificuldade de controle dos níveis de glicemia em pacientes mais jovens e uma necessidade de um controle mais rigoroso com intervenção medicamentosa nesta população estudada Os níveis glicêmicos em pacientes não diabéticos internados por AVCH e AVCI foi semelhante.