Intracranial hemangiomas are uncommon, especially in the absence of diffuse hemangiomatosis or the syndrome consisting of posterior fossa malformations, hemangiomas, arterial anomalies, coarctation of the aorta and cardiac defects, eye abnormalities, sternal clefting, and/or supra-umbilical raphe (PHACES). We saw an 8-month-old ex-premature girl with a large left-sided ocular and facial hemangioma that had been growing since early infancy. Examination revealed a 7 x 13 cm violaceous tumor involving the left periocular region and face. Ophthalmologic examination revealed deprivation amblyopia, anisometropia with myopia and astigmatism. Magnetic resonance imaging demonstrated a vascular tumor mass involving the scalp, face, and calvarium with extension into the orbit, infratemporal fossa, nasopharynx, lateral medullary cistern, internal auditory canal, and fourth ventricle. Marked enhancement was seen with contrast, and no posterior fossa malformations were noted. She was treated with prednisolone, which was tapered over 12 months. Follow-up magnetic resonance imaging examination at 25 months showed a marked decrease in the size of all lesions, with residual hemangioma in the periorbital soft tissues and small foci in the orbit and intracranial sites. The brain and ventricular system were normal. Intracranial hemangioma may occur in the setting of a large facial hemangioma (especially segmental) in the absence of the PHACES syndrome or diffuse hemangiomatosis. Radiological imaging should be considered to assess for intracranial hemangioma as well as posterior fossa or arterial anomalies.
4-(3-(Trifluoromethyl)benzylthio)phthalonitrile (1) was synthesized. Metal-free phthalocyanine 2, zinc(II) phthalocyanine 3 and cobalt(II) phthalocyanine 4 were synthesized starting with dinitrile compound 1. Photodynamic therapy properties of 2 and 3 were studied.
Chemical hazards are at the forefront of the sources of danger that adversely affect the health and safety of employees in working environments. Gaseous chemicals, which are classified as simple asphyxiant, irritant and chemical asphyxiant, carry serious risks for the working environment.
In this study, it is aimed to determine the carboxyhemoglobin (COHb) levels of gasoline distributors, taxi-bus drivers and automotive industry workers in Gümüşhane province, which are exposed to exhaust gases, and to propose occupational health and safety (OHS) measures for them to work in a healthy and safe environment.
In the study, blood samples were taken from the workers who were exposed to CO due to their profession and from the control group who were not exposed to CO, and their COHb saturation percentages were determined by the CO-Oximetry device. An 11-question semi-structured questionnaire was applied to determine the relationships between COHb levels, smoking habits, professional experience, and whether or not they received OHS training, and the results were evaluated with the SPSS program.
As a result of the study, significant differences were revealed between the COHb levels of those exposed to exhaust gas and the control group. When variables such as %COHb levels and the professional experience of the employees, whether they have received OHS training or not, are examined, it is seen that these variables do not affect the result.
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