It is still a major challenge for preparing semiconductor nanocrysals with controllable size, shape, and doping. Especially, the size of nanoparticles under 10 nm still remains a big challenge. To date, there are very few researches of the synthesis of SnO 2 nanocrystals by using biomolecule-assisted hydrothermal approach. SnO 2 is an n-type semiconductor with the free exciton Bohr radius of 2.7 nm. The degradation of rhodamine B (RhB), an organic dye, in aqueous suspension is selected as a probe reaction to evaluate the catalytic activity of semiconductor photocatalytic performance. Herein, we report a biomolecule-assisted hydrothermal route for generating SnO 2 with diameters <10 nm, which presents excellent photocatalytic degradation of RhB. Under the basic condition, the degradation of RhB is close to 100% within 150 min. The high degradation rate of RhB on the as-synthesized SnO 2 nanocrystals can be attributed to the small size. The degradation mechanism is also discussed.

Fangcang shelter hospitals were established in China during the coronavirus disease 2019 (COVID-19) pandemic as a countermeasure to stop the spread of the disease. To our knowledge, no research has been conducted on mental health problems among patients in Fangcang shelter hospitals. This study aimed to determine the prevalence and major influencing factors of anxiety and depressive symptoms among COVID-19 patients admitted to Fangcang shelter hospitals. From February 23, 2020, to February 26, 2020, we obtained sociodemographic and clinical characteristics information of COVID-19 patients in Jianghan Fangcang Shelter Hospital (Wuhan, China) and assessed their mental health status and sleep quality. Data were obtained with an online questionnaire. The questionnaire consisted of a set of items on demographic characteristics, a set of items on clinical characteristics, the Self-Rating Anxiety Scale, Self-Rating Depression Scale, and Pittsburgh Sleep Quality Index. Three hundred seven COVID-19 patients who were admitted to Jianghan Fangcang Shelter Hospital participated in this study. The prevalence of anxiety and depressive symptoms were 18.6% and 13.4%, respectively. Poor sleep quality and having � two current physical symptoms were independent risk factors for anxiety symptoms. Female sex, having a family member with confirmed COVID-19, and having � two current physical symptoms were independent risk factors for depressive symptoms. Anxiety and depressive symptoms were found to be common among COVID-19 patients in Fangcang Shelter Hospital, with some patients being at high risk.

Hyperlipidemia, defined as the presence of excess fat or lipids in the blood, has been considered as a high-risk factor and key indicator of many metabolic diseases. The gut microbiota has been reported playing a vital role in regulating host lipid metabolism. The pathogenic role of gut microbiota in the development of hyperlipidemia has been revealed through fecal microbiota transplantation experiment to germ-free mice. The effector mechanism of microbiota-related metabolites such as bile acids, lipopolysaccharide, and short-chain fatty acids in the regulation of hyperlipidemia has been partially unveiled. Moreover, studies on gut-microbiota-targeted hyperlipidemia interventions, including the use of prebiotics, probiotics, fecal microbiota transplantation, and natural herbal medicines, also have shown their efficacy in the treatment of hyperlipidemia. In this review, we summarize the relationship between gut microbiota and hyperlipidemia, the impact of gut microbiota and microbiota-related metabolites on the development and progression of hyperlipidemia, and the potential therapeutic management of hyperlipidemia targeted at gut microbiota.

Lung cancer is the most common cause of cancer-related mortality worldwide. It is a complex disease involving multiple genetic and epigenetic alterations. The development of transcriptomics revealed the important role of long non-coding RNAs (lncRNAs) in lung cancer occurrence and development. Here, microarray analysis of lung adenocarcinoma tissues showed the abnormal expression of lncRNA RGMB-AS1. However, the role of lncRNA RGMB-AS1 in lung adenocarcinoma remains largely unknown. We showed that upregulation of lncRNA RGMB-AS1 was significantly correlated with differentiation, TNM stage, and lymph node metastasis. In lung adenocarcinoma cells, downregulation of lncRNA RGMB-AS1 inhibited cell proliferation, migration, invasion, and caused cell cycle arrest at the G1/G0 phase. In vivo experiments showed that lncRNA RGMB-AS1 downregulation significantly suppressed the growth of lung adenocarcinoma. The expression of lncRNA RGMB-AS1 was inversely correlated with that of repulsive guidance molecule b (RGMB) in lung adenocarcinoma tissues, and UCSC analysis and fluorescence detection assay indicated that lncRNA RGMB-AS1 may be involved in the development of human lung adenocarcinoma by regulating RGMB expression though exon2 of RGMB. In summary, our findings indicate that lncRNA RGMB-AS1 may play an important role in lung adenocarcinoma and may serve as a potential therapeutic target.

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Dimethyl-and diphenylsilylene add stereospecifically to cis-and trons-2-butene to give the corresponding siliranes. Easy additions to cyclopentene and cyclohexene indicate that the cycloadditions are cis. Opening of the siliranes by methanol also occurs in stereospecifically cis fashion.

Complex Mg(OH)2 nanostructures are synthesized via a biomolecule-assisted hydrothermal route. The as-synthesized Mg(OH)2 nanostructures are dispersed into an acrylonitrile-butadiene-styrene (ABS) copolymer by mechanical kneading, which shows an excellent flame-retardant behavior. Also we demonstrated for the first time that the complex Mg(OH)2 nanostructures can find application in self-cleaning for its superhydrophobicity with water contact angle over 150° and sliding angle of 1°.

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