3,5-Diarylisoxazoles and 1,3,5-triarylpyrazolines are synthesized via Michael addition of "hydroxylamine hydrochloride, phenylhydrazine" respectively over chalcones followed by cyclization using K 2 CO 3 as solid support. Reactions are shown to be highly regioselective regardless of the nature of the substituent in the substrates and afforded single isoxazole and pyrazoline isomer in excellent yields.
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Imidazole derivatives R 0190Environmentally Benign Approach to Imidazole-2-thiones. -A microwave-promoted synthesis of substituted imidazolethiones (III) (12 examples) from benzoin (I) and substituted thioureas (II) is achieved under solvent-free conditions . -(KIDWAI*, M.; KUKREJA, S.; RASTOGI, S.; SINGHAL, K.; Indian J. Chem., Sect.
A green route for the synthesis of multi-substituted 2,3-dihydro-xanthenone derivatives using ionic liquid as solvent and amino acid as promoter is described. The reaction is simple and proceeds well at room temperature and devoid of the use of any harmful catalyst or solvent. This is an efficient technique.Key words: xanthene, ionic liquid, glycine, room temperature.
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