Unilateral condylar hyperplasia is characterised by slow progressive growth of the different parts of mandible, the aetiology of which is still unclear. It is a self-limiting condition mostly seen between the age of 11–30 years causing facial asymmetry and its progression ceases after a certain time. In literature until now very few cases have been reported and every case that is being reported adds to its features or the aetiology. Previously, it has been classified into two types that is, hemimandibular hyperplasia and hemimandibular elongation. Here, we report a similar case with a few features distinct from those reported earlier.
Laser intervention prevents recurrence and restricts malignant transformation, and also reduces post-operative dysfunctions. Post-laser therapy recurrence is reported as ranging from 7.7-38.1% and malignant transformation as ranging from 2.6-9% (Ishii et al., 2003; Ishii et al., 2004). The advantages of using laser in treatment of oral lesions includes; the haemostatic effect (giving a clear field of operation), brief therapeutic intervention, reduced traumatization of adjoining tissues (reduced inflammatory
CorrespondenceTO THE EDITOR, British Journal of Venereal Diseases Inhibition of gonococci by a selective medium: disparity between isolates from sexual partners Sir, A proportion of clinical isolates of Neisseria gonorrhoeae fail to grow on selective medium containing vancomycin, colistin, nystatin, and trimethoprim (VCNT). Reyn and Bentzon (1972) and Brorson et al. (1973) reported the isolation frequency of these strains to be about 4 % and 100% respectively and found vancomycin to be the inhibitory component. The sensitivity of these strains to vancomycin has been attributed to env mutations which result in phenotypic hypersensitivity to antibiotics including vancomycin (Sparling et al., 1976). Observations in this department suggest that other mechanisms may also be involved in the inhibition of certain gonococcal isolates by vancomycin.The isolation and identification of gonococci have been previously described (Platt, 1976a). Ready-poured bi-plates, containing GC selective medium (VCNT) and GC non-selective medium, were obtained from Gibco-Biocult (Paisley, Scotland) and each batch was quantitatively quality-controlled to ensure consistent inhibitory activity. The isolation frequency of VCNT-sensitive gonococci remained constant at between 4 % and 6 %.Gonococci were isolated from 32 patients attending the department of genitourinary medicine at the West London Hospital. From four (25 %) patients and their respective sexual partners gonococci were isolated which grew on non-selective medium but failed to grow on selective medium on both primary isolation and subsequent subculture. Gonococci isolated from a further 12 patients failed to grow on selective medium on primary isolation; of these six were male and six were female.On subculture each of five isolates tested produced colonies on selective medium which were similar in size and number to a control plate lacking VCNT. The gonococci isolated from each of the 12 sexual partners grew well on selective medium on primary isolation.Reyn and Bentzon (1972) found that about 40 % of strains, inhibited by vancomycin on primary isolation, were capable of growth on subculture if a heavy inoculum was used, and they attributed this result to random variation in the original inocula and a 'training effect' during laboratory subculture. The high proportion (75 %) of disparate vancomycin sensitivity between sexual partners on primary isolation and the resistance of the vancomycin-sensitive isolates on subsequent subculture suggests that an alternative mechanism is involved.Although env mutations have been demonstrated in clinical isolates of N. gonorrhoeae (Eisenstein and Sparling, 1978), for vancomycin sensitivity to be solely under env control would require both isolates from sexual partners to exhibit similar sensitivity to VCNT. The results obtained from four pairs of patients are compatible with this hypothesis. The disparate results obtained with 24 paired isolates may be explained as a function of the physiological state of the organism in vivo. For many organ...
Aims and Objective: The present study aimed to evaluate 2 bone graft materials, that is, biphasic hydroxyapatite and β-tricalcium phosphate, in the treatment of periodontal vertical bony defects. In term of attachment level, probing depth and radiographic bone level changes. Also, a new digital method of radiographic assessment was used for measurement of vertical bone defect. Material and Methods: Ten subjects with periodontitis and having two or more vertical bony defects were enrolled in the study. Patients were classified randomly into 2 groups. Group I consisted of the experimental site where defect was filled with biphasic hydroxyapatite and β-tricalcium phosphate graft and Group II consisted of control site where only the open flap debridement (OFD) was carried out. Clinical parameters were evaluated at baseline, 3 and 6 months; Radiographs were taken at baseline and 6 months after surgery. Results: Overall, by the end of 6 months, biphasic hydroxyapatite and β-tricalcium phosphate and OFD treatment groups exhibited a significant reduction in probing depth almost by 75% and gain in clinical attachment level at follow-up. In the biphasic hydroxyapatite and β-tricalcium phosphate group, radiographic bone level gain appeared to be greater than in the OFD group. Conclusion: In the present study, biphasic hydroxyapatite and β-tricalcium phosphate have shown promising results and have showed reduction in probing depth, a resolution of osseous defects and gain in clinical attachment level when compared to open flap debridement.
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