Hyperuricemia is associated with an increased risk of NAFLD in Asian populations. Further prospective cohort studies are needed to assess the impact of hyperuricemia on the risk of NAFLD in Western countries.
Helicobacter suis has a greater tendency to induce gastric mucosa-associated lymphoid tissue lymphoma compared with other Helicobacter species in humans and animals. Saccharomyces boulardii has been established as an adjunct to H. pylori eradication treatment, but the effect of S. boulardii administration alone on Helicobacter infection remains unclear. Here, we found that S. boulardii administration effectively decreased the bacterial load of H. suis and inhibited the formation of lymphoid follicles in the stomach post-infection. The levels of H. suis-specific immunoglobulin A (IgA) and secretory IgA in the gastric juice and small intestinal secretions and the production of mouse β-defensin-3 in the small intestinal secretions were significantly increased by S. boulardii administration at 12 weeks after H. suis infection. In addition, feeding with S. boulardii inhibited the expression of inflammatory cytokines and lymphoid follicle formation-related factors after H. suis infection. These results suggested that S. boulardii may be useful for the prevention and treatment of Helicobacter infection-related diseases in humans.
Residential energy consumption (REC) has become increasingly important in constructing an energy-saving and environment-friendly society in China. The main purpose of this study is to provide a more in-depth analysis of the determinants of REC from an urban-rural segregation perspective, and quantify the contributions of individual determinants to the regional disparities of REC. Based on the extended STIRPAT (the stochastic impacts by regression on population, affluence, and technology) model, seemingly unrelated regression (SUR) estimation is employed to examine the impacts of various determinants of urban REC per capita (URECP) and rural REC per capita (RRECP) in a sample of China’s 30 provinces over the period 2007–2016. Then, following the results of SUR, this paper tries to explore the reasons for interprovincial disparities of URECP and RRECP by using the Shapley value decomposition. The empirical results show that income level and heating lead to an increase in URECP, while other factors, including the share of natural gas, average temperature, child dependency ratio and gross dependency ratio, significantly decrease URECP. In terms of RRECP, it is shown that old-age dependency ratio, income level and the share of coal consumption positively influence RRECP, while average temperature has a negative effect on RRECP. Specially, the effect of gross dependency ratio on RRECP is positive, indicating the non-working-age population causes more energy use than the working-age population in rural areas. According to the Shapley decomposition, rather than social-economic variables, climate and heating factors contribute the most to the interprovincial differences in URECP. Furthermore, it is found that income level is the most important factor accounting for inter-provincial differences in RRECP. The findings of this research are of great interest, not only to scholars in REC-related fields, but also to decision makers.
In order to improve the application value of natural microcrystalline graphite with carbon content of 49.5%, high-purity microcrystalline graphite was prepared by emulsifying kerosene flotation firstly, and then purifying hydrofluoric acid and hexafluorosilicic acid. Then the purified microcrystalline graphite was prepared for the lithium-ion battery anode material, its microstruture and electrochemical properties were analyzed, the purification mechanism and lithium storage mechanism were discussed. The research results show that carbon content of microcrystalline graphite after emulsified kerosene flotation and mixed acid purification are 93.5% and 99.0% respectively. After pickling, high-purity microcrystalline graphite shows the largest layer spacing, which is 0.351 5 nm and is 0.001 4 nm higher than that of natural microcrystalline graphite. Size disparity of acid washing sample is larger, layered structure is more obvious, cycle performance and magnification performance are better than those of floation sample. The pickled sample has the highest initial reversible specific capacity of 477.4 mAh/g, and the first Coulomb efficiency is 61.3%. Charge transfer impedance, interface impedance and SEI membrane impedance, and lithium ion diffusion impedance in electrode material are significantly lower than those of microcrystalline graphite after flotation.
Helicobacter suis colonizes the stomachs of a variety of animals, including humans, and is more likely than other Helicobacter species to induce gastric mucosa-associated lymphoid tissue lymphoma. Obesity is a low-grade chronic inflammatory state in which the induction of a chemokine network contributes to a variety of diseases. However, the effect of obesity on the development of gastric MALT in the presence of H. suis infection remains unclear. Here, we reveal that high-fat-diet-induced obesity upregulates the expression of lymphoid chemokines in the stomach and accelerates the H. suis infection-induced formation of gastric lymphoid follicles, potentially via a mechanism that involves the activation of the nuclear factor kappa B (NF-κB) signaling pathway. These findings provide novel insight into the pathogenesis of obesity-related diseases, especially those induced by Helicobacter infection.
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