Spermine and spermidine serve as the key biomarkers for early-stage cancer diagnosis. This work reports a rapid, highly selective, and noninvasive sensing platform for spermine/spermidine. The hybrid material, developed in this work, has been characterized by UV–vis, IR, powder XRD, SEM, EDX, and rheological studies. Storage modulus (G′) and loss modulus (G″) measurements infer that embedding boronic acid integrated coumarin softens the agarose gel fibers at room temperature. Stress resistance measurement and subsequent imaging further confirms the softness of the hybrid hydrogel over pure agarose gel and homogeneous distribution of the dye in the hybrid matrix as well. The soft hydrogel with a limit-of-detection (LOD) value of 6 μM showed a nearly 27-fold fluorescence enhancement for spermine. The hybrid hydrogel matrix can be useful within a wide concentration window (6 μM–2.5 mM spermine). Response time (≤7 s) confirms rapid detection ability of the material. Noninterference from various metal ions, common anions, monosaccharides, nucleobases, and amino acids, particularly, histidine, arginine, lysine, ornithine, glutamine, etc.,  makes the hybrid hydrogel suitable for the real-time measurement of spermine in human urinary and blood samples. Furthermore, noninterference from other biogenic amines supports the highly selective nature of the hybrid gel. The ability to measure spermine in urinary samples by the probe offers a noninvasive nature of the sensing platform. Overall, we envisioned that the hybrid material formulation would be useful for diagnosing early-stage tumors and assessing the recovery of patients undergoing chemotherapeutic treatment.

In this Introduction, we set the Special Issue on 'Tropical Imaginaries and Climate Crisis' within the context of a call for relational climate discourses as they arise from particular locations in the tropics. Although climate change is global, it is not experienced everywhere the same and has pronounced effects in the tropics. This is also the region that experienced the ravages – to humans and environments – of colonialism. It is the region of the planet’s greatest biodiversity; and will experience the largest extinction losses. We advocate that climate science requires climate imagination – and specifically a tropical imagination – to bring science systems into relation with the human, cultural, social and natural. In short, this Special Issue contributes to calls to humanise climate change. Yet this is not to place the human at the centre of climate stories, rather we embrace more-than-human worlds and the expansion of relational ways of knowing and being. This paper outlines notions of tropicality and rhizomatics that are pertinent to relational discourses, and introduces the twelve papers – articles, essays and speculative fiction pieces – that give voice to tropical imaginaries and climate change in the tropics.

Background This scoping review aimed to overview studies that used administrative data linkage in the context of child maltreatment to improve our understanding of the value that data linkage may confer for policy, practice, and research. Methods We searched MEDLINE, Embase, PsycINFO, CINAHL, and ERIC electronic databases in June 2019 and May 2020 for studies that linked two or more datasets (at least one of which was administrative in nature) to study child maltreatment. We report findings with numerical and narrative summary. Results We included 121 studies, mainly from the United States or Australia and published in the past decade. Data came primarily from social services and health sectors, and linkage processes and data quality were often not described in sufficient detail to align with current reporting guidelines. Most studies were descriptive in nature and research questions addressed fell under eight themes: descriptive epidemiology, risk factors, outcomes, intergenerational transmission, predictive modelling, intervention/service evaluation, multi-sector involvement, and methodological considerations/advancements. Conclusions Included studies demonstrated the wide variety of ways in which data linkage can contribute to the public health response to child maltreatment. However, how research using linked data can be translated into effective service development and monitoring, or targeting of interventions, is underexplored in terms of privacy protection, ethics and governance, data quality, and evidence of effectiveness.

War has been instrumental in destroying land and forests and thus is a major contributor to climate change. Degradation due to war has been especially significant in Africa. The African continent, once green, is now almost denuded of its rich forests and pillaged of its precious natural resources due to the brutality of colonisation and more recent postcolonial civil wars. In Sierra Leone the civil war continued for over eleven years from 1991 to 2002 and wrought havoc on the land and forests. Thus the anxiety and trauma suffered by the people not only includes the more visible aspects of human brutality, but also the long lasting effects of ecocide which relate to climate change. Underlying narratives that address traumatic ecological disasters is a sense of anxiety and depression resulting from the existential threat of climate change. This paper demonstrates how narratives can metaphorically represent both ecocide and climate change and argues that such stories help people in tackling the real life stresses of  anxiety and trauma. To establish the argument this paper has drawn on scientific and sociological data and placed these vis-à-vis narrative episodes in Aminatta Forna’s novels Ancestor Stones (2006) and The Memory of Love (2010). In these novels Forna depicts the ecological crisis that colonisation and civil war have wrought on Sierra Leone. The anxiety and post-traumatic stress disorder – of war and ecocide – suffered by the fictional Sierra Leonean characters are explained through Cathy Caruth’s trauma theory.

This paper argues that difficult relationships in human life followed by memories, introspection, retrospection, foreshadow, flashback, and awful remembrances are coloured by pain and trauma. Unresolved trauma affects the way one perceives others and oneself in relation to others, which has a significant impact on relationships and often results in behaviour that is not conducive to healthy relationships. Complicated, disordered feelings and distressing emotions that give rise to anxiety find an expression in relationships, either overtly or covertly. This paper will focus on how the characters, suffering from anxiety due to stressed relationships, in the short stories in The Progress of Love, written by Alice Munro, employ defence mechanisms to repress their trauma and project a different version of themselves as responsible individuals who are capable of leading a normal life. The dialectic of trauma covertly present in the narrative will be unravelled using Judith Herman’s theory of trauma. Further, this analysis will investigate and foreground how the underlying trauma finds indirect expression in complicated relationships.

Since the publication of Arran Stibbe's critically acclaimed book Ecolinguistics: Language, Ecology, and the Stories We Live By (2015), a new approach to ecolinguistics has emerged, one that focuses on how much ecologically constructive or destructive views are included in the discourses contained in the "stories" that people "live by" every day. Toni Morrison, expanding the possibilities of African American ecological writing, explores the healing impact of nature that is reflected in the "stories" the characters "live by" in her novels. Her writings build a narrative frame in which nature is the benefactor and healer. On the one hand the narratives poignantly and painfully expose the psychological or emotional wounds suffered by the African- Americans and on the other depict nature as a healer of these wounds. Our concern in this paper is Morrison’s novel Home (2012). It is a story of a veteran soldier, Frank Money who returns home, with traumatic war memories deeply entrenched into his mind, to rescue his sister Cee from the clutches of a doctor who was abusing her body. The siblings  are ultimately healed by associating themselves with and communicating with other members of their community and nature. This paper will apply Stibbe’s theory of ecolinguistics and look at the stories and narrative discourses in Morrison’s Home to see how the ecology of language in the narrative posits that living in harmony with nature produces a healing effect.

This paper attempts to locate Hughes’s poetic diction as Ecriture feminine since like feminist poetry the diction of his poetry is rebellious and questions the hierarchical structure of society where White people hold more power and promote the idea of racial superiority. His desire to express the angst of the Blacks finds currency in the definition and explication of feminine writing. The focus of this paper will be on analysis of the poetry of Langston Hughes in the light of ecriture feminine in order to show how Hughes counters hegemony’s repressive rhetoric, challenges the loss of agency through the language of the dominant class and recreates another symbolic order.

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