CommentaryHuman body has its own mechanism of healing known as whole body healing. Each healthy cell of human body emit photon, disease is an altered emission of photons. Inside and outside of our body consists of energy. Photons from our cells jump on to others and counter photons may be vibrating at other place is known as quantum entanglement and quantum tunnelling. The concept of aduality states that matter can be converted in to energy and energy can be converted in to matter proposed by Nobel laureate Hans-Peter Dürr. Most of all diseases start in mind ends in mind. Mind is nothing but a part of human consciousness, is a canvas, on which our thoughts are projected. It is a holographic presentation of human body. Mind has a blue print of human body. Body tries to rebuild each time, when it oscillate between energy and particle 1044 times in a second. Human body is a holographic projection of human consciousness. With our positive thoughts or consciousness known as quantum thinking, which creates energy, with a genuine intention to heal, known as quantum healing akin to self healing or auto healing.Pranic healing, meditation, chi therapy with our positive thoughts, genuine intention to heal known as quantum thinking and healing takes place at spiritual level by producing endorphins [1].Endorphins are neuropeptides, endogenous morphine produced by pituitary gland and hypothalamus, receptors are present in brain and on immune cells. Endogenous opioids includes β-endorphins, enkephalins, and dynorphins, operate via µ-opioid receptor. Beta endorphin is the abundant endorphins secreted and synthesized by anterior pituitary gland, it is a precursor of protein proopiomelanocortin (POMC) [2]. It has got immune-stimulatory, anti-inflammatory, stress buster, euphoric, and analgesic activity. Immune-stimulatory due to activation of NK cells and macrophages producing IFN-ϒ, opsonin, granzyme-B, has an antiviral activity and anti-inflammatory activity.Anti-inflammatory activity is due to activation of IFN-ϒ and IL -18 and suppressing TNF-α, IL-1, IL-6 pro-inflammatory cytokines, suppress free radical release such as ROS, RNS and also suppressing key transcriptional factors NF-KB, STAT-3, which is involved in tumor progression by cell proliferation, cell survival, angiogenesis, immune suppression, genomic instability, invasion, metastasis [3][4][5]. Also involved in autoimmune diseases by immune suppression, conversion of Th1 type lymphocyte to Th2 type, activation of proteolytic enzymes like MMPs (matrix metalloproteases) results in cellular changes ,tissue damage, and chronic inflammatory conditions by activating cytokines such as IL-1, TNF-α, . Stress buster activity by reducing cortisol, neuropeptides through HPA axis (hypothalamo-pituitary adrenal axis) and inhibiting activation of sympathetic nervous system and activation of parasympathetic nervous system of autonomic nervous system, which is involved in anti-inflammatory activity and peripheral immunity [10][11][12][13]. Euphoric activity by inhibiting an inhibitor...

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Microbial & Biochemical Technology J o u rn al of M ic ro b ia l & Bioc h e m ic a l Te chno lo g y

Endorphins are natural neuropeptides secreted by anterior pituitary gland through hypothalamus in response to stress full conditions such as physical exercise, yoga and meditation. Stress is also a one of the predisposing factor for cancer by activating inflammatory mediators such as IL-1 and TNF-α, involved in tumor progression. It has stress buster activity by reducing cortisol, analgesic activity by inhibiting substance P, euphoric activity by releasing dopamine and immune-stimulatory activity by activating NK cells, macrophages. It can be used for natural antitumor activity by activating NK cells, macrophage innate immune cells, and has anti-inflammatory activity by inducing IL-12, IL-8 cytokines. It has got it's receptors on the immune cells, binding of endogenous opioids such as beta endorphin to the receptors on the immune cells, activates immune cells. This article briefs about the role of Beta endorphin on cancers and its anticancer activities.

Human body works as a whole, has an excellent capacity to heal by itself. Holistic healing is a whole body healing yields better results without adverse effects, inexpensive, unlike reductionist view of healing. Inside and outside of our body consists of energy. Most of all diseases are starts in mind, mind is the canvas, on which our thoughts are projected, is a part of human consciousness. Mind is the holographic representation of the human body. With our positive thoughts, genuine intention to heal known as quantum thinking and healing takes place at spiritual level by producing endorphins. Endorphins are opioid peptides, has many activities such as immune stimulatory, anti-inflammatory, stress buster activity, anti-aging, and alteration in gene expression , can be used to treat many diseases like cancer , auto-immune diseases, and infectious diseases. This article highlights about current concept of holistic healing is quantum healing and application in treatment of diseases.

Growing concerns of probiotics in recent times is due to their wide spectrum of activities with harmless effects compared to antibiotics. Live microorganisms ingested in certain quantity is beneficial for the health of human beings for their vast and versatile mechanism of actions from preventive and therapeutic action for reducing inflammation, infection and in cancer prevention by their immune stimulatory activity, anti-cancer activity and anti-microbial activity . Probiotics role in dentistry is limited and used in the treatment of various diseases is put forth in this article. Can probiotics replace antibiotics in near future in this antibiotic resistance era.

Cancer is a major threat to mankind, mainly caused by external environmental factors such as tobacco, alcohol and chemicals. Cancer cells work like normal cells. Normal cells to become cancer cell, it must undergo tumor initiation, tumor promotion, tumor progression. Cancer cells circulate through out human body by seeding, in this case can we detect the cancer early. How early? This article highlights about controversies related to early detection of cancer.

Endorphins are endogenous morphine, neuropeptide. There are three types of endorphins such as beta-endorphins, enkephalins, dynorphins are produced during stress and pain. Receptors of endorphins are situated on nervous system and immune cells. It has got various activities such as immune stimulatory, anti-inflammatory, and delay aging by reduction of free radicals (ROS, RNS) production by immune cells during oxidative burst. This article brief's about the novel roles of endorphins in anti-aging activity.