AIM: To analyse the characteristics, and analyse the impact of pharmacist intervention on quality of life (QOL) outpatients with type 2 diabetes mellitus (T2DM). METHODS: This six-month analytical cohort study was conducted by assessing the patients’ characteristics and their quality of life by distributing a questionnaire, and the 36-Item short form instrument to the patients with T2DM (n = 45) admitted to the Tertiary hospital in Tebing Tinggi. Patients who had mental disorders, HIV-AIDS, liver disease, stage 4 chronic kidney disease, and pregnant women were excluded from the study. The patients’ quality of life was measured before and after interventions and analysed using the paired t-test. All analyses were performed using the Statistical Package for the Social Sciences (SPSS, version 22, Chicago, IL, USA) (p < 0.05 was considered significant). RESULTS: The mean age of the patients was 61.96 ± 6.45 (years). Most (66.7%) of them were females. The mean QOL (in the score) of the patients: before the intervention, 61.07 ± 15.13; after the intervention, 70.15 ± 14.23, there was a significant difference between groups with and without interventions, p < 0.001. CONCLUSION: Active contribution of pharmacists in the management of T2DM patients is urgent and important to improve the patients’ QOL.
Complications caused by diabetes are becoming a more serious problem so controlling blood glucose intensively can reduce diabetes mortality by reducing complications that arise. This study aims to determine the characteristics of Type II Diabetes Mellitus Patients at Tuan Rondahaim Regional General Hospital, Simalungun Regency in 2019 With this type of research Descriptively, this research was carried out at the Tuan Rondahaim Regional General Hospital, Simalungun Regency from July to September 2019 with a total population of 40 people using the sampling technique, namely total sampling where all populations are sampled. The results of this study indicate that the younger a person has diabetes mellitus, it can be seen that the lower the number of people with diabetes mellitus,the number of people with diabetes mellitus is more suffered by women, there are fluctuations in the duration of the disease in the Toba and Simalungun tribes, while in the Javanese the longer they suffer from diabetes mellitus, there is a decrease in the incidence of duration of the disease with adherence to taking medication that has no significant difference compared to Duration of disease with adherence to diet There was a significant difference between adherents and non-adherents.where the tendency is not to comply with dict rules It is expected that Efarina University through the Bachelor of Nursing study program can provide counseling about Diabetes Mellitus, specifically Type II Diabetes Mellitus both in the community and in hospitals. adjusted to the portion and condition of the patient in this study, it can be included in the information that has been conveyed by researchers regarding type II Diabetes Mellitus sufferers.
The background in this study is that Dengue Hemorrhagic Fever (DHF) is a public health problem in Indonesia, since 1968 the number of cases has tended to increase and its spread has become wider. The incidence of Dengue Hemorrhagic Fever (DHF) in the working area of the Pematang Raya Health Center in 2008 was recorded as many as 91 cases with 2 fatalities. From the data obtained, it is known that there was a significant increase in the incidence of Dengue Hemorrhagic Fever (DHF) from year to year between 2004-2008. The purpose of this study was to determine what health behaviors were associated with the occurrence of Dengue Hemorrhagic Fever (DHF) in the working area of the Pematang Raya Public Health Center. This type of research was an analytic survey study using a case-control approach. The population in this study were Dengue Hemorrhagic Fever sufferers (cases) and not Dengue Hemorrhagic Fever sufferers (controls). A sample of 40 cases and 40 controls were obtained using simple random sampling technique. The instruments used in this study were 1) questionnaires, 2) data on DHF patients at the Pematang Raya Health Center and DKK Kendal. The data for this study were obtained from primary data, in the form of interview results, and secondary data in the form of DHF patients at the Pematang Raya Health Center and DKK Kendal. The data obtained in this study were analyzed using the Chi-square statistical test formula and the determination of the Odds Ratio (OR). From the research results it was found that the significant factors were: cleaning the water reservoir (p value-0.044, OR=2.513), closing the water reservoir (p value 0.002, OR=4.333), draining water reservoirs (p value 0.004, OR=3.857), burying used goods (p value 0.014, OR-3.095), throwing garbage in its place and burning it (p value-0.043, OR=2.538), hanging clothes (p value=0.001, OR=4.896), and use mosquito repellent lotion (p value=0.002, OR=6.000). From the results of the research and discussion, it can be concluded that health behaviors related to the incidence of Dengue Hemorrhagic Fever (DHF) in the 2018 Pematang Raya Health Center work area, namely cleaning water reservoirs, closing water reservoirs, draining water reservoirs, burying used goods , throwing trash in its place and burning it, hanging clothes, and wearing mosquito repellent.
The cat's whiskers plant is empirically used by the community for the treatment of gout and rheumatism. This research was conducted with the aim of knowing the anti-inflammatory power of cat's kumis (Orthosihon stamineus Benth) leaf extract. This study was a quasi-experimental study with a one-way completely randomized design. Kumis Kucing leaf extract was extracted using 70% ethanol. A total of 25 male wistar rats aged 2-3 months, weighing 150-200g were divided into 5 groups. Each group was treated orally with distilled water (negative control), diclofenac sodium 2.25 mg/kg BW (positive control). Kumis leaf ethanol extract tested at doses of 123, 245 and 490 mg/kgBB. Treatment 1 hour before the feet of rats were inflamed with 1% sublantar carrageenin. Measurements of the rat's foot volume were carried out every 0.5 hours for 6.5 hours. The obtained average edema volume curve is used to calculate AUC (Area Under The Curve) and the obtained AUC is used to calculate DAI (Anti-Inflammatory Power). The AUC and DAI data were tested statistically with one way Anava and followed by LSD with a 95% confidence level. The results showed that the ethanol extract of Kumis Kucing leaves had an anti-inflammatory effect on male white rats of the Wistar strain. Kumis Kucing ethanol extract at doses of 123, 245 and 490 mg/kg BW yielded 33.11%; 52.64% and 64.12% respectively. The results showed that the ethanol extract of Kumis Kucing leaves had an anti-inflammatory effect on male white rats of the Wistar strain. Kumis Kucing ethanol extract at doses of 123, 245 and 490 mg/kg BW yielded 33.11%; 52.64% and 64.12% respectively. The results showed that the ethanol extract of Kumis Kucing leaves had an anti-inflammatory effect on male white rats of the Wistar strain. Kumis Kucing ethanol extract at doses of 123, 245 and 490 mg/kg BW yielded 33.11%; 52.64% and 64.12% respectively.
Diabetes melitus (DM) merupakan masalah kesehatan global yang insidensinya semakin meningkat. Sebanyak 346 juta orang di dunia menderita diabetes, dan diperkirakan mencapai 380 juta jiwa pada tahun 2025. Menurut WHO tahun 2000, Indonesia menempati peringkat keempat negara dengan prevalensi diabetes terbanyak di dunia dengan jumlah penderita sebesar 8,4 juta orang. Tujuan penelitian ini adalah untuk mengetahui pola penggunaan obat diabetes mellitus di RSU Harapan Pematangsiantar periode Januari-Maret 2020 serta mengevaluasi penggunaan obat antidiabetes yang meliputi ketepatan indikasi, tepat dosis, tepat pasien, tepat obat, dan tepat cara pemberian. Penelitian ini berupa penelitian survei dengan metode retrospektif, desain yang digunakan adalah cross sectional, yaitu pengumpulan data variabel untuk mendapatkan gambaran penggunaan obat antidiabetes pada pasien rawat inap RSU Harapan Pematangsiantar periode Januari-Maret 2020. Hasil penelitian menunjukkan menunjukkan bahwa pasien yang menderita diabetes mellitus di RSU Harapan periode Januari-Maret 2020 lebih banyak perempuan dibandingkan dengan laki-laki, dengan jumlah perempuan 25 pasien (55,6%) dan laki-laki 20 pasien (44,4%). Distribusi pemakaian obat antidiabetes yang tertinggi adalah Glimepiride pemberian tunggal yaitu 11 peresepan (24,4%) dan kombinasi yang tertinggi adalah Glimepiride dengan Metformin 5 peresepan (11,1%). Hasil evaluasi rasionalitas menyatakan bahwa pemakaian obat antidiabetes telah tepat indikasi, tepat dosis, tepat pasien, tepat obat dan tepat cara pemberian. Kata Kunci: Diabetes mellitus, antidiabetes, evaluasi rasionalitas, RSU Harapan.
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