Background: Despite significant advances in canine cataract surgery over the years, many post-operative complications persist and reduces the success rate of phacoemulsification procedure. The aim of current study was to evaluate post-operative complications encountered till 90 days after bimanual phacoemulsification with implantation of different acrylic Intraocular Lenses.Methods: The study was conducted on 24 canine eyes. All the clinical cases were subjected to detailed ocular, ultrasonography and neuro-ophthalmic tests for ascertaining cataract and associated neuro-ophthalmic pathology. Dogs were divided in four groups with 6 eyes in each group and subjected to phacoemulsification procedure for removal of cataractous lens and implanted with square edge or round edge hydrophilic or hydrophobicintra ocular lenses.Result: Statistically non-significant (p£0.05) variations were found for all the post- operative complications among the groups. Within the groups initially higher values were recorded and on subsequent days a declining trend of varying degrees were observed. The corneal opacity was a major postoperative complication leading to failure to achieve vision with other coinciding neuro-ophthalmic conditions.
Background: To evaluate use of homologous platelet rich plasma (PRP) drop and leucocyte-platelet rich fibrin (L-PRF) clot/membrane as regenerative therapy for healing of corneal ulcer in dogs and its subsequent comparison with conventional therapy. Methods: In this randomized study, 30 dogs were divided into three groups of 10 animals each. It was ensured each group had grade I, II and III ulcers. Group I received medicinal treatment with antimicrobial and non-steroidal anti-inflammatory eye drop. In Group II PRP drops and in Group III L-PRF membrane was used to evaluate corneal ulcer healing. Homologous platelet concentrates were prepared in laboratory and used for assessment of healing on various grades of corneal ulcer on basis on reduction in size and depth of ulcer, presence of stromal infiltration, scleral involvement, corneal opacity and vascularization. Result: Post treatment, the size of corneal ulcer started to reduce gradually from day 7 onwards. Significant (p≤0.05) reduction was observed from day 10 in group I after instillation of drops Moxifloxacin and Flurbiprofen and in group II after instillation of PRP. It was measured as 5.35 ± 0.63 and 5.20 ± 0.98 mm at day 0, which reduced significantly (p≤0.05) to 3.90 ± 0.50 and 3.10 ± 0.98 mm at day 10 in group I and group II respectively. In group III there was significant reduction in size of ulcer from day 0 to day 7 measuring 7.80 ± 1.05 and 0.20 ± 0.11mm respectively. Thereafter, from day 10 onwards complete sealing of ulcer was observed in all the cases. Post treatment there was no significant reduction in corneal opacity from day 0 to day 30 in group I dogs and corneal opacity persisted specially in grade II and grade III ulcers. There was significant reduction (p≤0.05) in opacity from 2.90 ± 0.35 to 2.10 ± 0.38 and 3.00 ± 0.37 to 2.40 ± 0.34 in group II and group III dogs from day 0 to day 10 respectively. In group I, II and III there was significant (p≤0.05) reduction in vascularization from 1.50±0.30 to 1.20±0.13, 1.30±0.37 to 0.60±0.22 and 1.40±0.31 to 0.40±0.31 from day 0 to day 15 respectively. There was a significant reduction in vascularization on day 15 in group II and group III compared to group I animals.
Background: Canine oral fibrosarcomas are locally invasive malignant mesenchymal tumors and the third most frequently occurring neoplasia of oral cavity of dogs. The present study was conducted to record pathological features of oral fibrosarcomas in canines. Methods: During the study period (September 2020- April 2021), a total of 18 cases of canine oral neoplasia were reported and amongst these fibrosarcoma was diagnosed in five animals (27.78%). The blood samples were collected from all the dogs and the excised tumor mass was processed at Department of Veterinary Pathology, Co.V.Sc. and A.H., Jabalpur. Result: The hematological profile of all the five dogs showed no variation however; serum biochemical analysis revealed hypercalcemia. The serum MDA concentration was elevated in dogs with fibrosarcoma, indicating oxidative stress. The gross morphology of the tumors included red to pink colored irregular masses, hard in consistency and firmly attached to the underlying tissue. Cytologically, the impression smears revealed spindle shaped cells with round to elongated nuclei along with strands of collagen fibres. Upon histopathological examination proliferation of fibrous connective tissue was observed in the sub-mucosa. Higher magnification revealed several immature spindle shaped fibroblasts along with scanty amounts of collagenous matrix. Masson’s trichome staining also exhibited blue stained collagen deposition. Mitotic figures were numerous (8.4 mitosis/10 hpf). The tissue sections stained by modified silver colloid staining were examined at 1000 x magnification. Mean Ag-NOR count of the silver nitrate stained tissue sections was enumerated to be 9.15 dots/nucleus. Immunohistochemical examination detected CD31 immunopositivity in the tissue sections as brown staining of the infiltrating blood vessels, indicating neovascularization of the tumor.
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