Objectives To investigate the relationship between the nuchal translucency (NT) thickness and crown -rump length (CRL) in normal Asian fetuses during the first trimester. Design

Background This study aims to evaluate the efficacy and safety of the induction of labour in mid-trimester pregnancy using a double-balloon catheter (DBC) within 12 h versus within 12–24 h. Methods In this retrospective study, a total of 58 pregnant women at 14 + 0 weeks to 27 + 6 weeks of gestation were enrolled as research subjects, and they underwent the intended termination of pregnancy at our birth centre from January 1, 2017, to June 31, 2019. Based on the duration of DBC, the patients were divided into two groups, namely, the DBC group within 12 h and the DBC group within 12–24 h. Results All 58 cases were successful vaginal deliveries, and no one chose to undergo caesarean section. The success rate of induction (successful abortion of the foetus and placenta without the implementation of dilation and evacuation) was higher in the DBC group within 12–24 h (96.3%, 29/31) than in the DBC group within 12 h (71.0%, 18/27) (p < 0.05). Additionally, the time from DBC removal to delivery in the DBC group within 12–24 h was significantly shorter than that in the DBC group within 12 h (3.0 h versus 17.8 h) (p < 0.05), and the degree of cervical dilation after DBC removal in the DBC group within 12–24 h was larger than that in the DBC group within 12 h (p < 0.05). Conclusion In the clinic, the placement time of DBC generally lasts for approximately 12 h. However, considering that the cervical condition is immature in the mid-trimester, properly extending the placement time of DBC to 24 h will benefit cervical ripening and reduce the chance of dilation and evacuation.

Background: Prenatal bleeding is very dangerous for pregnant women with placenta previa during termination of pregnancy in the mid-trimester. Traditionally, cesarean section or hysterectomy is used to stop bleeding. This study aims to investigate the method for termination of mid-trimester pregnancy with placenta previa, especially emergency uterine artery embolization (UAE) combined with cervical double balloon (CDB).Methods: A retrospective study was conducted based on 261 cases of mid-pregnancy termination in our hospital, where 34 cases with placenta previa were set as the observation group, and the remaining 227 cases were set as control group. At first, the termination method of Mifepristone combined with Misoprostol/Ethacridine Lactate was adopted. If the volume of prenatal bleeding was up to 400 mL, emergency uterine artery embolization (UAE) was implemented to stop bleeding, then cervical double balloon (CDB) was used to promote cervical ripening. Receiver operating characteristic (ROC) curves analysis was performed to assess the accuracy in predicting the length of placental edge crossed the cervical os for prenatal bleeding.Results: The number of gravidity/parities, the rate of cesarean section, the medical cost, the rate of previous cesarean section were all higher in the observation group than in the control group (P < .05). The volume of prenatal hemorrhage, postpartum hemorrhage, the rate of puerperal morbidity, emergency UAE rate and ICU rate were higher in the observation group than in the control group (P < .05). There were 4 cases showing prenatal hemorrhage up to 400 mL and undergoing emergency UAE + CDB in the observation group, while there were no such cases in the control group (P < .05). An optimal cut-off value of 1.7cm for the length of placental edge crossed the cervical os in diagnosing prenatal hemorrhage demonstrated sensitivity and specificity of 75.0% and 86.7%, respectively (area under the ROC curve, 0.858). Conclusion:The combined therapy of mifepristone and Misoprostol/Ethacridine Lactate was useful for termination of midtrimester pregnancy with placenta previa, and attention needs to be attached to prenatal hemorrhage during labor induction. Emergency UAE + CDB is a good combination method to treat prenatal hemorrhage and promote cervical ripening during the induction.

Objective: Investigate the different methods for termination at mid-trimester in pregnant women with placenta previa. Methods: A retrospective study was conducted on 264 cases for termination at mid-pregnancy in our hospital, and 34 cases with placenta previa were set as the observation group, and 230 cases with normal placenta were set as control group. Among them, the preferred methods of termination at first were Mifepristone combined with Misoprostol/Rivanol in the observation group, and Mifepristone combined with Misoprostol/Rivanol/cervical double balloon (CDB) in the control group. If the volume of prenatal bleeding was up to 100 mL in the observation group, emergency artery embolization (UAE) was implemented to stop bleeding, then CDB plus with curettage were used in order. If it failed to induce in the control group, CDB was used subsequently followed with Misoprostol/Rivanol. Then, all those cases were set as the comprehensive-induce group, and the others were set as the simple-induce group.Results: the average maternal age, the number of gravidity/parities, the rate of cesarean section, the hospitalization days and cost, the induction time, the rate of postpartum hemorrhage, puerperal infection were higher in the observation group than those in the control group(p<0.05). There were 4 cases used UAE+CDB+curettage in the observation group and 6 cases used CDB after Misoprostol/Rivanol in the control group. The duration time of termination, the rate of postpartum hemorrhage and transferring to ICU, hospitalization days and cost in the comprehensive-induce group were significantly higher than those in the simple-induce group (p<0.05). All cases were delivered through vaginal successfully.Conclusion: We should pay more attention to the complications of prenatal bleeding, postpartum hemorrhage, puerperal infection during the induction at mid-trimester in pregnant women with placenta previa. Emergency UAE + CDB +curettage is a good combination method in prenatal hemorrhage of placenta previa during termination, and CDB was a good tool for cervical ripen with immature cervical condition in mid-trimester for induction of labor.

Background Pregnancy termination in the second trimester is a complex and delicate situation for patients with complete placenta previa (CPP), which has less been reported. The objective of this research was to investigate and evaluate the clinical effect of uterine artery embolization(UAE) combined with cervical double balloon(CDB) for patients with CPP. Methods We conducted a retrospective study based on a large medical center. The medical records of patients who were diagnosed with CPP and treated UAE combined with CDB for termination in the second trimester in our hospital from January 2017 and March 2021 were retrospectively reviewed. The clinical outcomes were analyzed.Results A total of 11 patients with CPP were included in this study. Prenatal diagnosis of CPP was realized by trans-vaginal ultrasound. The average age was 34.2 years old, and the gestational week was 21.6 weeks. Of the selected patients, 3 cases (3/11) had previous caesarean delivery, 5 cases were at older maternal age (≥35 years old), 10 cases underwent emergency UAE for prenatal bleeding equal or up to 400 mL and 1 case underwent prophylactic UAE for placenta percreta, and all cases underwent CDB to promote cervical ripening. It was worth noting that 5 cases (5/11) of selected patients underwent curettage to take out fetus and placenta. The uterus preservation was achieved in all 11 patients. The complications associated with conservative management included prenatal hemorrhaging (10/11), blood transfusion (5/11), fever (2/11), and septicemia (1/11). The mean dilation of cervix was from 0cm to 1.9cm, the length of cervix was from 3.5cm to 0.6cm and the Bishop scores were from 1.5 to 7.3 after using CDB, the changes of cervical conditions were statistically significant (p＜0.05). The levels of WBC and CRP were higher after termination with medicine+UAE+CDB and/or curettage. Conclusion The adjuvant therapy of UAE, CDB, and/curettage step by step is a preferred choice for patients with CPP who underwent pregnancy termination in the second trimester.

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Digital media is a good way for more people to express their opinions. This article uses the literature research method to explore how mothers and feminist mothers use digital media to empower themselves. It is found that the development of digital media allows feminist voices to be raised so that mothers can gain more rights to speak. It also helps mothers fight for gender equality in childcare. However, social media is presented in different ways in different online environments. The result shows that the argument and digital media increase the class difference between mothers and blurs the power of mothers. Therefore, the integration of maternal rights and feminism is progressive but limited.

Background This study aims to evaluate the efficacy and safety of the induction of labour in mid-trimester pregnancy using double-balloon catheter (DBC) within 12 hours versus within 12–24 hours. Methods In this retrospective study, a total of 58 pregnant women with gestation age of 14 + 0 weeks to 27 + 6 weeks were enrolled as research objects, and they underwent intended termination of pregnancy at our birth center from January 1, 2017, to June 31, 2019. Based on the duration time of DBC, the cases were divided into two groups (DBC group within 12 hours and DBC group within 12–24 hours). Results All of the 58 cases were successful vaginal delivery and no one chose cesarean section. The success rate of induction (successful abortion of fetus and placenta without the implementation of dilatation and evacuation) was higher in the DBC group within 12–24 hours (96.3%, 29/31) than that in DBC group within 12 hours (71.0%, 18/27) (p < 0.05). At the same time, the time from DBC removal to delivery in 12–24 hours DBC group was significantly shorter than that in DBC group within 12 hours (3.0 h versus 17.8 h) (p < 0.05), the degree of cervical dilation after DBC removal in DBC group within 12–24 hours was larger than that in DBC group within 12 hours (p < 0.05). Conclusion In the clinic, the placement time of DBC is generally lasting for about 12 hours. However, considering the cervical condition is immature in the mid-trimester, properly extending the placement time of DBC to 24 hours will benefit for cervical ripening and lead to reduce chance of dilatation and evacuation.